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Protease Domain

Known as: Proteolytic Domain 
The portion of a proteolytic protein which causes hydrolysis and cleavage of other protein polypeptides.
National Institutes of Health

Related topics

Related topics

50 relations
ADAM15 protein, humanADAM17 protein, humanADAM8 protein, humanADAMTS1 protein, human

Papers overview

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Highly Cited
2009
Highly Cited
2009
Hepatitis C virus NS2 is a protease stimulated by cofactor domains in NS3
Chronic infection with hepatitis C virus (HCV) affects 130 million people worldwide and is a major cause of liver cirrhosis and… 
Highly Cited
2005
Highly Cited
2005
HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells.
Highly Cited
2003
Highly Cited
2003
Crystal structure of the CUB1‐EGF‐CUB2 region of mannose‐binding protein associated serine protease‐2
Serum mannose‐binding proteins (MBPs) are C‐type lectins that recognize cell surface carbohydrate structures on pathogens, and… 
Review
2002
Review
2002
The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes.
Mannan-binding lectin (MBL) and ficolins (L-ficolin and H-ficolin) initiate the lectin pathway of complement activation upon… 
Highly Cited
1999
Highly Cited
1999
Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains
Abstract We cloned and sequenced a mouse gene encoding a new type of membrane bound serine protease (epithin) containing a… 
Review
1998
Review
1998
Hepatitis C virus NS3/4A protease.
Highly Cited
1997
Highly Cited
1997
Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi.
Recent identification of a C3-like gene in sea urchins revealed the presence of a complement system in invertebrates. To… 
1993
1993
Cloning of the PABA peptide hydrolase alpha subunit (PPHα) from human small intestine and its expression in COS‐1 cells
Highly Cited
1992
Highly Cited
1992
The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits.
Highly Cited
1989
Highly Cited
1989
Increasing gene expression in yeast by fusion to ubiquitin.
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