Skip to search formSkip to main contentSkip to account menu

Protease Domain

Known as: Proteolytic Domain 
The portion of a proteolytic protein which causes hydrolysis and cleavage of other protein polypeptides.
National Institutes of Health

Related topics

Related topics

50 relations
ADAM15 protein, humanADAM17 protein, humanADAM8 protein, humanADAMTS1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
The Cysteine Protease Domain of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Possesses Deubiquitinating and Interferon Antagonism Functions
ABSTRACT Porcine reproductive and respiratory syndrome (PRRS) virus nonstructural protein 2 (nsp2) contains a cysteine protease… 
Highly Cited
2007
Highly Cited
2007
Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus
Severe acute respiratory syndrome coronavirus (SARS-CoV) is a novel coronavirus that causes a highly contagious respiratory… 
Highly Cited
2007
Highly Cited
2007
Crystal Structure of the NS3 Protease-Helicase from Dengue Virus
ABSTRACT Several flaviviruses are important human pathogens, including dengue virus, a disease against which neither a vaccine… 
Highly Cited
2002
Highly Cited
2002
G protein–coupled receptors
  • 2002
  • Corpus ID: 14294885
Highly Cited
2002
Highly Cited
2002
c‐FLIPL is a dual function regulator for caspase‐8 activation and CD95‐mediated apoptosis
Activation of the caspase cascade is a pivotal step in apoptosis and can occur via death adaptor‐mediated homo‐oligomerization of… 
Highly Cited
2000
Highly Cited
2000
Cellular Localization of Membrane-type Serine Protease 1 and Identification of Protease-activated Receptor-2 and Single-chain Urokinase-type Plasminogen Activator as Substrates*
Membrane-type serine protease 1 (MT-SP1) was recently cloned, and we now report its biochemical characterization. MT-SP1 is… 
Highly Cited
1999
Highly Cited
1999
The Serine Protease and RNA-Stimulated Nucleoside Triphosphatase and RNA Helicase Functional Domains of Dengue Virus Type 2 NS3 Converge within a Region of 20 Amino Acids
ABSTRACT NS3 protein of dengue virus type 2 has a serine protease domain within the N-terminal 180 residues. NS2B is required for… 
Highly Cited
1999
Highly Cited
1999
Corin, a Mosaic Transmembrane Serine Protease Encoded by a Novel cDNA from Human Heart*
A novel cDNA has been identified from human heart that encodes an unusual mosaic serine protease, designated corin. Corin has a… 
Highly Cited
1998
Highly Cited
1998
Identification and Characterization of the Structural and Transporter Genes for, and the Chemical and Biological Properties of, Sublancin 168, a Novel Lantibiotic Produced by Bacillus subtilis 168*
An antimicrobial peptide produced byBacillus subtilis 168 was isolated and characterized. It was named sublancin 168, and its… 
Highly Cited
1997
Highly Cited
1997
Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3.
To contribute to the development of the transcription map of human chromosome 21 (HC21), we have used exon trapping from pools of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)