Protease Domain

Known as: Proteolytic Domain 
The portion of a proteolytic protein which causes hydrolysis and cleavage of other protein polypeptides.
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
The activation of matriptase requires proteolytic cleavage at a canonical activation motif that converts the enzyme from a one… (More)
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Highly Cited
2002
Highly Cited
2002
Molecular chaperones and proteases monitor the folded state of other proteins. In addition to recognizing non-native… (More)
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Highly Cited
2001
Highly Cited
2001
Thrombotic thrombocytopenic purpura is associated with acquired or congenital deficiency of a plasma von Willebrand factor… (More)
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Highly Cited
2000
Highly Cited
2000
Memapsin 2 (beta-secretase) is a membrane-associated aspartic protease involved in the production of beta-amyloid peptide in… (More)
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Highly Cited
2000
Highly Cited
2000
The cDNAs of two new human membrane-associated aspartic proteases, memapsin 1 and memapsin 2, have been cloned and sequenced. The… (More)
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Highly Cited
1999
Highly Cited
1999
NS3 protein of dengue virus type 2 has a serine protease domain within the N-terminal 180 residues. NS2B is required for NS3 to… (More)
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Review
1998
Review
1998
ADAMs are proteins containing a disintegrin and metalloproteinase domain. Several important insights were provided in the past… (More)
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Highly Cited
1996
Highly Cited
1996
An estimated 1% of the global human population is infected by hepatitis C viruses (HCVs), and there are no broadly effective… (More)
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Highly Cited
1989
Highly Cited
1989
We propose through a sequence and structural-pattern analysis that a protein domain of undefined function encoded by the… (More)
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Highly Cited
1987
Highly Cited
1987
Several human bacterial pathogens, including the Gram-negative diplococcus Neisseria gonorrhoeae, produce extracellular proteases… (More)
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