Procainamide

Known as: p-Amino-N-(2-diethylaminoethyl)benzamide, Amide, Procaine, Procainamida 
A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
CpG island hypermethylation occurs in most cases of cancer, typically resulting in the transcriptional silencing of critical… (More)
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Highly Cited
2004
Highly Cited
2004
Imatinib is a tyrosine kinase inhibitor that is effective in the treatment of chronic myeloid leukemia (CML). Not all patients… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE The purpose of this study is to evaluate the demethylating and tumor suppressor-reactivating activity of hydralazine and… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND A mutation in the cardiac sodium channel gene (SCN5A) has been described in patients with the syndrome of right bundle… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Atrial fibrillation (AF) can be initiated by ectopic beats originating from the atrial or great venous tissues. This… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Atrial fibrillation (AF) shortens the atrial effective refractory period (ERP) and predisposes to further episodes of… (More)
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Highly Cited
1993
Highly Cited
1993
Human antigen-specific CD4+ T cells become autoreactive after treatment with various DNA methylation inhibitors, including 5… (More)
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Highly Cited
1990
Highly Cited
1990
Procainamide and hydralazine inhibit T cell DNA methylation and induce autoreactivity in cloned CD4+ T cells. These drugs also… (More)
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Highly Cited
1988
Highly Cited
1988
Inhibitors of DNA methylation, such as 5-azacytidine, induce gene expression. We have previously reported that cloned T cells… (More)
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Highly Cited
1975
Highly Cited
1975
A new lidocaine derivative (Astra, GEA 968) depresses excitability of myelinated frog nerve in a manner which depends upon the… (More)
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