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Pravastatin
Known as:
Pravastatine
, [1S-[1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha]]-1,2,6,7,8,8a-Hexahydro-beta,!d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid
, Pravastatin [Chemical/Ingredient]
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A synthetic lipid-lowering agent. Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which…
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National Institutes of Health
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Related topics
Related topics
33 relations
Broader (4)
Anticholesteremic Agents
Enzyme Inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Naphthalenes
Narrower (11)
CS-514
Lin-Pravastatin
Prareduct
Pravachol
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Coronary Artery Disease
Drug Allergy
Hepatic Metabolism [PK]
Hypercholesterolemia
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
[Erythrocyte aggregation in patients with arterial hypertension and dyslipidemia treated with pravastatin].
Medvedev In
,
Skoriatina Ia
Klinicheskaia meditsina
2014
Corpus ID: 40594809
The aim of the study was to evaluate effect of pravastatin therapy on erythrocyte aggregation in patients with arterial…
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2007
2007
Effects of pravastatin on ventricular remodeling by activation of myocardial KATP channels in infarcted rats: role of 70-kDa S6 kinase
T. Lee
,
M-S Lin
,
Chang‐Her Tsai
,
N. Chang
Basic Research in Cardiology
2007
Corpus ID: 25258714
AbstractReactive cardiomyocyte hypertrophy after myocardial infarction is an important risk factor for arrhythmias. Myocardial…
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1999
1999
Lipid modification and coronary heart disease in type 2 diabetes: different from the general population?
M. Feher
,
R. Elkeles
Heart
1999
Corpus ID: 21992912
Patients with non-insulin dependent (type 2) diabetes have a 2–5-fold increase in age adjusted mortality from coronary heart…
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1998
1998
BEHANDELING EN PREVENTIE VAN CORONAIRE HARTZIEKTEN DOOR VERLAGING VAN DE SERUMCHOLESTEROLCONCENTRATIE ; DERDE CONSENSUS 'CHOLESTEROL'
M. Simoons
,
A. Casparie
1998
Corpus ID: 73311284
textabstractDe consensustekst betreffende een verhoogde cholesterolconcentratie is voor de tweede maal herzien. In angiografische…
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Review
1998
Review
1998
Pravastatin-induced lichenoid drug eruption.
Keough Gc
,
Richard G. W. tt
,
Grabski Wj
1998
Corpus ID: 53804567
Although drug eruptions caused by pravastatin and other lovastatin analogs have previously been described, reports of lichenoid…
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1998
1998
Altitude-induced migraine headache secondary to pravastatin: case report.
Ramsey Cs
,
Snyder Qc
1998
Corpus ID: 68326258
A 46-yr-old airline captain with many exposures to altitude chamber, fighter, and airliner flight developed migraine-type…
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1997
1997
Regression of transplant coronary artery disease during chronic low-density lipoprotein-apheresis.
Park Jw
,
M. Merz
,
P. Braun
The Journal of Heart and Lung Transplantation
1997
Corpus ID: 22933637
BACKGROUND The pathogenesis of transplant coronary artery disease (TxCAD) is probably multifactorial. Immune mechanisms may be…
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Highly Cited
1996
Highly Cited
1996
Differential Effects of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors on the Development of Myopathy in Young Rats
J. Reijneveld
,
R. Koot
,
J J Bredman
,
J. A. Joles
,
P. R. Bär
Pediatric Research
1996
Corpus ID: 23925645
HMG-CoA reductase inhibitors (statins), cholesterol-lowering drugs that have not been approved for use in children and…
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1994
1994
Microbial metabolites affecting lipid biosynthesis
S. Ōmura
,
H. Tomoda
1994
Corpus ID: 51274115
Abstract
1993
1993
Efficacy and tolerability of simvastatin 20 mg vs pravastatin 20 mg in patients with primary hypercholesterolemia. European Study Group.
Lambrecht Lj
,
Malini Pl
1993
Corpus ID: 75405655
The safety, tolerability, and efficacy of 20 mg daily doses of simvastatin and pravastatin were compared in this double-blind…
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