Pravastatin

Known as: Pravastatine, [1S-[1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha]]-1,2,6,7,8,8a-Hexahydro-beta,!d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid, Pravastatin [Chemical/Ingredient] 
A synthetic lipid-lowering agent. Pravastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
OBJECTIVE The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Evidence-based treatment for hypercholesterolaemia in Japan has been hindered by the lack of direct evidence in this… (More)
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Highly Cited
2003
Highly Cited
2003
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Although statins reduce coronary and cerebrovascular morbidity and mortality in middle-aged individuals, their… (More)
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Highly Cited
2001
Highly Cited
1998
Highly Cited
1998
BACKGROUND We studied whether inflammation after myocardial infarction (MI) is a risk factor for recurrent coronary events and… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Although diabetes is a major risk factor for coronary heart disease (CHD), little information is available on the… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND In patients with high cholesterol levels, lowering the cholesterol level reduces the risk of coronary events, but the… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Lowering the blood cholesterol level may reduce the risk of coronary heart disease. This double-blind study was… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Hypercholesterolemia is common after cardiac transplantation and may contribute to the development of coronary… (More)
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