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CS-514

Known as: CS 514, CS514 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
BackgroundStatins are extensively used for cardiovascular disease prevention. Statins reduce mortality rates more than other… 
Highly Cited
1990
Highly Cited
1990
Nine patients with heterozygous familial hypercholesterolaemia were treated for eight weeks with either 40 mg pravastatin or… 
Highly Cited
1989
Highly Cited
1989
Pravastatin sodium (CS-514) is a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a key enzyme in… 
Highly Cited
1987
Highly Cited
1987
CS-514 is a metabolic product of compactin and has a potent cholesterol-lowering effect in vitro and in animal studies by… 
Highly Cited
1987
Highly Cited
1987
HMG-CoA reductase catalyzes the conversion of hydroxymethylglutarate to mevalonate, an important early rate-limiting step in the…