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Pravastatin Sodium

Known as: Pravastatin Sodium Salt, Pravastatin Sodium [Chemical/Ingredient], Sodium Salt, Pravastatin 
The sodium salt of pravastatin with cholesterol-lowering and potential antineoplastic activities. Pravastatin competitively inhibits hepatic… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (4)

CS-514PravacholRMS-431SQ-31000
Coronary Artery DiseaseDrug AllergyHepatic Metabolism [PK]Hypercholesterolemia

Papers overview

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Highly Cited
2011
Highly Cited
2011
Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: Open-label, randomized study*
Objective:To investigate whether the use of pravastatin reduces the frequency of ventilator-associated pneumonia and whether it… 
Highly Cited
2010
Highly Cited
2010
Buccal Drug Delivery of Pravastatin Sodium
The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal tablets of pravastatin sodium… 
2010
2010
Effect of pravastatin on experimental diabetic wound healing.
Highly Cited
2004
Highly Cited
2004
Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses.
BACKGROUND In randomized trials of secondary prevention, pravastatin sodium and aspirin reduce risks of cardiovascular disease… 
Highly Cited
2001
Highly Cited
2001
Pravastatin Improves Cerebral Vasomotor Reactivity in Patients With Subcortical Small-Vessel Disease
Background and Purpose— Recent investigations have suggested an important role of statins in the prevention of stroke and… 
Highly Cited
1999
Highly Cited
1999
Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions.
Highly Cited
1999
Highly Cited
1999
Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on oxidative modification of human low-density lipoprotein in vitro.
Highly Cited
1995
Highly Cited
1995
Reduction of serum cholesterol levels alters lesional composition of atherosclerotic plaques. Effect of pravastatin sodium on atherosclerosis in mature WHHL rabbits.
We examined whether serum cholesterol reduction alters the lesional composition of atherosclerotic plaques. To reduce serum… 
Highly Cited
1991
Highly Cited
1991
Biotransformation of pravastatin sodium in humans.
Pravastatin sodium (PV) is a potent cholesterol-lowering agent that acts by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A… 
Highly Cited
1990
Highly Cited
1990
Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects.
Pravastatin sodium, a competitive inhibitor of HMG-CoA reductase, is a new orally effective hypocholesterolaemic agent. In a two… 
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