FAQ

Pravastatin Sodium

Known as: Pravastatin Sodium Salt, Pravastatin Sodium [Chemical/Ingredient], Sodium Salt, Pravastatin 
The sodium salt of pravastatin with cholesterol-lowering and potential antineoplastic activities. Pravastatin competitively inhibits hepatic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
024619882018

Related topics

Related topics

15 relations

Narrower (4)

CS-514PravacholRMS-431SQ-31000
Coronary Artery DiseaseDrug AllergyHepatic Metabolism [PK]Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Pravastatin Sodium
Drug Allergy
Coronary Artery Disease
Pregnancy
Hypercholesterolemia
Lactation

Papers overview

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2011
2011
Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study.
OBJECTIVE To investigate whether the use of pravastatin reduces the frequency of ventilator-associated pneumonia and whether it… (More)
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2010
2010
Buccal Drug Delivery of Pravastatin Sodium
The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal tablets of pravastatin sodium… (More)
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2001
2001
Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease.
BACKGROUND AND PURPOSE Recent investigations have suggested an important role of statins in the prevention of stroke and dementia… (More)
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2000
2000
Long-term assessment of psychological well-being in a randomized placebo-controlled trial of cholesterol reduction with pravastatin. The LIPID Study Investigators.
BACKGROUND There is controversial evidence that a low serum cholesterol level is associated with an increased risk of depression… (More)
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1996
1996
Effects of different inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, pravastatin sodium and simvastatin, on sterol synthesis and immunological functions in human lymphocytes…
It has been shown previously that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (HMG-CoA RIs) such as compactin and… (More)
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1995
1995
Reduction of serum cholesterol levels alters lesional composition of atherosclerotic plaques. Effect of pravastatin sodium on atherosclerosis in mature WHHL rabbits.
We examined whether serum cholesterol reduction alters the lesional composition of atherosclerotic plaques. To reduce serum… (More)
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1992
1992
Disposition and metabolism of pravastatin sodium in rats, dogs and monkeys
Pravastatin sodium (pravastatin) is a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, and was… (More)
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1991
1991
Biotransformation of pravastatin sodium in humans.
Pravastatin sodium (PV) is a potent cholesterol-lowering agent that acts by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A… (More)
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1990
1990
Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects.
Pravastatin sodium, a competitive inhibitor of HMG-CoA reductase, is a new orally effective hypocholesterolaemic agent. In a two… (More)
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1990
1990
Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Tissue selectivity of pravastatin sodium (pravastatin) in inhibition of cholesterol synthesis was investigated and its effect was… (More)
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