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Pravastatin Sodium
Known as:
Pravastatin Sodium Salt
, Pravastatin Sodium [Chemical/Ingredient]
, Sodium Salt, Pravastatin
The sodium salt of pravastatin with cholesterol-lowering and potential antineoplastic activities. Pravastatin competitively inhibits hepatic…
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National Institutes of Health
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Related topics
Related topics
15 relations
Narrower (4)
CS-514
Pravachol
RMS-431
SQ-31000
Coronary Artery Disease
Drug Allergy
Hepatic Metabolism [PK]
Hypercholesterolemia
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: Open-label, randomized study*
D. Makris
,
Efstratios Manoulakas
,
+5 authors
E. Zakynthinos
Critical Care Medicine
2011
Corpus ID: 25650673
Objective:To investigate whether the use of pravastatin reduces the frequency of ventilator-associated pneumonia and whether it…
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Highly Cited
2010
Highly Cited
2010
Buccal Drug Delivery of Pravastatin Sodium
S. Shidhaye
,
P. V. Thakkar
,
N. Dand
,
V. Kadam
AAPS PharmSciTech
2010
Corpus ID: 43847224
The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal tablets of pravastatin sodium…
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2010
2010
Effect of pravastatin on experimental diabetic wound healing.
T. Laing
,
R. Hanson
,
F. Chan
,
D. Bouchier‐Hayes
Journal of Surgical Research
2010
Corpus ID: 30335334
Highly Cited
2004
Highly Cited
2004
Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses.
C. Hennekens
,
F. Sacks
,
+11 authors
R. Belder
Archives of Internal Medicine
2004
Corpus ID: 3925583
BACKGROUND In randomized trials of secondary prevention, pravastatin sodium and aspirin reduce risks of cardiovascular disease…
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Highly Cited
2001
Highly Cited
2001
Pravastatin Improves Cerebral Vasomotor Reactivity in Patients With Subcortical Small-Vessel Disease
P. Sterzer
,
F. Meintzschel
,
A. Rösler
,
H. Lanfermann
,
H. Steinmetz
,
M. Sitzer
Stroke
2001
Corpus ID: 2683944
Background and Purpose— Recent investigations have suggested an important role of statins in the prevention of stroke and…
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Highly Cited
1999
Highly Cited
1999
Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions.
W. Kaesemeyer
,
R. Caldwell
,
J. Huang
,
R. Caldwell
Journal of the American College of Cardiology
1999
Corpus ID: 30494059
Highly Cited
1999
Highly Cited
1999
Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on oxidative modification of human low-density lipoprotein in vitro.
K. Suzumura
,
M. Yasuhara
,
K. Tanaka
,
T. Suzuki
Biochemical Pharmacology
1999
Corpus ID: 25186880
Highly Cited
1995
Highly Cited
1995
Reduction of serum cholesterol levels alters lesional composition of atherosclerotic plaques. Effect of pravastatin sodium on atherosclerosis in mature WHHL rabbits.
M. Shiomi
,
T. Ito
,
+7 authors
A. Tamura
Arteriosclerosis, Thrombosis and Vascular Biology
1995
Corpus ID: 25197273
We examined whether serum cholesterol reduction alters the lesional composition of atherosclerotic plaques. To reduce serum…
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Highly Cited
1991
Highly Cited
1991
Biotransformation of pravastatin sodium in humans.
D. Everett
,
T. Chando
,
G. Didonato
,
S. Singhvi
,
H. Pan
,
S. Weinstein
Drug Metabolism And Disposition
1991
Corpus ID: 41866796
Pravastatin sodium (PV) is a potent cholesterol-lowering agent that acts by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A…
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Highly Cited
1990
Highly Cited
1990
Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects.
S. Singhvi
,
H. Pan
,
R. A. Morrison
,
D. Willard
British Journal of Clinical Pharmacology
1990
Corpus ID: 3219147
Pravastatin sodium, a competitive inhibitor of HMG-CoA reductase, is a new orally effective hypocholesterolaemic agent. In a two…
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