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Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an… Expand CONTEXT
Obesity and diabetes are increasing in the United States.
To estimate the prevalence of obesity and diabetes… Expand Abundant data link hypercholesterolaemia to atherogenesis. However, only recently have we appreciated that inflammatory… Expand BACKGROUND
The objective of this study was to examine the association of Joint National Committee (JNC-V) blood pressure and… Expand CONTEXT
Although cholesterol-reducing treatment has been shown to reduce fatal and nonfatal coronary disease in patients with… Expand BACKGROUND
In patients with high cholesterol levels, lowering the cholesterol level reduces the risk of coronary events, but the… Expand BACKGROUND Lowering the blood cholesterol level may reduce the risk of coronary heart disease. This double-blind study was… Expand Indirect evidence suggests accelerated degradation of endothelium-derived nitric oxide (ENDO) by superoxide anion (O2-) in… Expand Apolipoprotein E (apoE) is a ligand for receptors that clear remnants of chylomicrons and very low density lipoproteins. Lack of… Expand Endothelial dysfunction is an early event in experimental studies of atherogenesis, preceding formation of plaques. We have… Expand