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Platelet-Derived Growth Factor Receptor
Known as:
Platelet Derived Growth Factor Receptors
, Receptor, PDGF
, Receptors, Platelet-Derived Growth Factor
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Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR…
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National Institutes of Health
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Related topics
Related topics
32 relations
Cell Proliferation Regulatory Process
Crenolanib Besylate
Dovitinib Lactate
Imatinib mesylate
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Narrower (1)
PDGFRL protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Autocrine/paracrine platelet-derived growth factor regulates proliferation of neural progenitor cells.
A. Erlandsson
,
K. Brännvall
,
S. Gústafsdóttir
,
B. Westermark
,
K. Forsberg-Nilsson
Cancer Research
2006
Corpus ID: 7231902
Growth factors play an important role in regulating neural stem cell proliferation and differentiation. This study shows that…
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Highly Cited
2003
Highly Cited
2003
SU 11248 Inhibits KIT and Platelet-derived Growth Factor Receptor in Preclinical Models of Human Small Cell Lung Cancer
T. Abrams
,
Leslie B. Lee
,
Lesley J. Murray
,
N. Pryer
,
J. Cherrington
2003
Corpus ID: 2001507
The purpose of this study was to evaluate the activity of the indolinone kinase inhibitor SU11248 against the receptor tyrosine…
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Highly Cited
1998
Highly Cited
1998
Activation of Src Family Members Is Not Required for the Platelet-Derived Growth Factor β Receptor To Initiate Mitogenesis
K. DeMali
,
A. Kazlauskas
Molecular and Cellular Biology
1998
Corpus ID: 35154901
ABSTRACT The basal activity of Src family kinases is readily detectable throughout the cell cycle and increases by two- to…
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Highly Cited
1996
Highly Cited
1996
Platelet-derived Growth Factor Induces a Long-term Inhibition of N-Methyl-D-aspartate Receptor Function*
C. Fernando Valenzuela
,
Z. Xiong
,
+6 authors
R. Harris
Journal of Biological Chemistry
1996
Corpus ID: 19482056
Platelet-derived growth factor (PDGF) is a multifunctional protein that plays important roles in many tissues, including the…
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1992
1992
Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma.
C. Walker
,
E. Bermudez
,
W. Stewart
,
J. Bonner
,
C. Molloy
,
J. Everitt
Cancer Research
1992
Corpus ID: 1506794
Although altered expression of platelet-derived growth factor (PDGF) is a hallmark of human mesothelioma, expression of PDGF…
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Highly Cited
1991
Highly Cited
1991
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine
J. Escobedo
,
D. R. Kaplan
,
W. Kavanaugh
,
C W Turck
,
L. T. Williams
Molecular and Cellular Biology
1991
Corpus ID: 22730497
Platelet-derived growth factor (PDGF) stimulates autophosphorylation of the PDGF receptor and association of the receptor with…
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Highly Cited
1991
Highly Cited
1991
Epidermal growth factor receptor, platelet-derived growth factor receptor, and c-erbB-2 receptor activation all promote growth but have distinctive effects upon mouse mammary epithelial cell…
D. Taverna
,
B. Groner
,
N. Hynes
Cell growth & differentiation : the molecular…
1991
Corpus ID: 33788251
Three different receptor tyrosine kinases, epidermal growth factor (EGF), c-erbB-2/neu, and platelet-derived growth factor (PDGF…
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Highly Cited
1990
Highly Cited
1990
Preferential inhibition of the platelet-derived growth factor receptor tyrosine kinase by staurosporine.
J. Secrist
,
I. Sehgal
,
G. Powis
,
R. Abraham
Journal of Biological Chemistry
1990
Corpus ID: 3132272
Ligand stimulation of the platelet-derived growth factor receptor (PDGF-R) results in rapid activation of the receptor tyrosine…
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Highly Cited
1988
Highly Cited
1988
Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor
J. Escobedo
,
P. Barr
,
L. Williams
Molecular and Cellular Biology
1988
Corpus ID: 22945397
Three types of mutations were introduced into the platelet-derived growth factor (PDGF) receptor to cause a loss of PDGF…
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Highly Cited
1988
Highly Cited
1988
Characterization of two monoclonal antibodies reactive with the external domain of the platelet-derived growth factor receptor.
L. Rönnstrand
,
L. Terracio
,
L. Claesson-Welsh
,
C. Heldin
,
K. Rubin
Journal of Biological Chemistry
1988
Corpus ID: 420252
Two monoclonal antibodies against the receptor for platelet-derived growth factor (PDGF) were obtained by immunizing mice with…
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