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Platelet-Derived Growth Factor Receptor

Known as: Platelet Derived Growth Factor Receptors, Receptor, PDGF, Receptors, Platelet-Derived Growth Factor 
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR… 
National Institutes of Health

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Cell Proliferation Regulatory ProcessCrenolanib BesylateDovitinib LactateImatinib mesylate

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PDGFRL protein, human

Papers overview

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Review
2018
Review
2018
Advances in studies of tyrosine kinase inhibitors and their acquired resistance
Protein tyrosine kinase (PTK) is one of the major signaling enzymes in the process of cell signal transduction, which catalyzes… 
Review
2007
Review
2007
Sunitinib: from rational design to clinical efficacy.
Sunitinib (SU011248) is an oral small molecular tyrosine kinase inhibitor that exhibits potent antiangiogenic and antitumor… 
Review
1996
Review
1996
Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways.
Highly Cited
1992
Highly Cited
1992
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.
Analysis of genomic organization and expression of platelet-derived growth factor receptors (PDGFR) and epidermal growth factor… 
Highly Cited
1992
Highly Cited
1992
Platelet-derived growth factor is angiogenic in vivo.
PDGF receptors have recently been found to be expressed in microvascular endothelium in vivo under circumstances of endothelial… 
Highly Cited
1991
Highly Cited
1991
Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.
We investigated whether platelet-derived growth factor (PDGF), or its receptor (PDGF-R), was upregulated in a rat model of… 
Highly Cited
1991
Highly Cited
1991
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine
Platelet-derived growth factor (PDGF) stimulates autophosphorylation of the PDGF receptor and association of the receptor with… 
Highly Cited
1990
Highly Cited
1990
Association between the PDGF receptor and members of the src family of tyrosine kinases
Review
1989
Review
1989
Signal transduction by the platelet-derived growth factor receptor.
When platelet-derived growth factor (PDGF) binds to its receptor on a quiescent fibroblast or smooth muscle cell, it stimulates a… 
Highly Cited
1988
Highly Cited
1988
Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C terminus.
The protein kinase domains of v‐kit, the oncogene of the acute transforming feline retrovirus HZ4‐FeSV (HZ4‐feline sarcoma virus… 
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