Phencyclidine

Known as: Dust, Angel, PCP, 1-(1-Phenylcyclohexyl)piperidine 
Developed as an anesthetic for humans in 1959. Its use was discontinued due to extreme side effects that included delirium, confusion, visual… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transient postnatal NMDA receptor blockade by phencyclidine (PCP), ketamine, or MK-801 induces developmental neuroapoptosis and… (More)
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Review
2007
Review
2007
Schizophrenia is a serious mental disorder that affects up to 1% of the population worldwide. As of yet, neurochemical mechanisms… (More)
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Highly Cited
2001
Highly Cited
2001
Both acute and chronic administration of N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and dizocilpine… (More)
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Highly Cited
1998
Highly Cited
1998
Glutamatergic abnormalities have been associated with several psychiatric disorders, including schizophrenia and addiction. Group… (More)
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Highly Cited
1998
Highly Cited
1998
The behavioral syndrome produced by phencyclidine (PCP) and its analog ketamine represents a pharmacological model for some… (More)
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Highly Cited
1997
Highly Cited
1997
The effects of the psychotomimetic drug phencyclidine on the neurochemistry and function of the prefrontal cortex in vervet… (More)
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Highly Cited
1997
Highly Cited
1997
Repeated ingestion of phencyclidine by humans induces enduring schizophrenic symptomatology, particularly cognitive dysfunction… (More)
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Highly Cited
1996
Highly Cited
1996
Rats learned to lever-press when such behavior was reinforced by microinjections of phencyclidine (PCP) directly into the… (More)
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Highly Cited
1989
Highly Cited
1989
Prepulse inhibition of the startle response occurs when a weak prestimulus precedes a startling stimulus and decreases the… (More)
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Highly Cited
1983
Highly Cited
1983
The interaction of two dissociative anaesthetics, ketamine and phencyclidine, with the responses of spinal neurones to the… (More)
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