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Phencyclidine

Known as: Dust, Angel, PCP, 1-(1-Phenylcyclohexyl)piperidine 
Developed as an anesthetic for humans in 1959. Its use was discontinued due to extreme side effects that included delirium, confusion, visual… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
  • D. Javitt
  • International review of neurobiology
  • 2007
  • Corpus ID: 32021523
Schizophrenia is a serious mental disorder that affects up to 1% of the population worldwide. As of yet, neurochemical mechanisms… Expand
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Review
2006
Review
2006
Tissue morphogenesis during development is dependent on activities of the cadherin family of cell-cell adhesion proteins that… Expand
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Review
1999
Review
1999
Several decades of research attempting to explain schizophrenia in terms of the dopamine hyperactivity hypothesis have produced… Expand
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Highly Cited
1998
Highly Cited
1998
Glutamatergic abnormalities have been associated with several psychiatric disorders, including schizophrenia and addiction. Group… Expand
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Highly Cited
1998
Highly Cited
1998
The behavioral syndrome produced by phencyclidine (PCP) and its analog ketamine represents a pharmacological model for some… Expand
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Highly Cited
1997
Highly Cited
1997
Subanesthetic doses of ketamine, a noncompetitive NMDA receptor antagonist, impair prefrontal cortex (PFC) function in the rat… Expand
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Highly Cited
1997
Highly Cited
1997
The effects of the psychotomimetic drug phencyclidine on the neurochemistry and function of the prefrontal cortex in vervet… Expand
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Highly Cited
1997
Highly Cited
1997
Repeated ingestion of phencyclidine by humans induces enduring schizophrenic symptomatology, particularly cognitive dysfunction… Expand
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Highly Cited
1983
Highly Cited
1983
1 The interaction of two dissociative anaesthetics, ketamine and phencyclidine, with the responses of spinal neurones to the… Expand
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Highly Cited
1978
Highly Cited
1978
During a 13-month period, 9 patients with phencyclidine-induced psychosis were admitted to Darnall Army Hospital. They exhibited… Expand
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