FAQ

Anesthetics, Dissociative

Known as: Dissociative Anesthetics, anesthetic, dissociative 
Intravenous anesthetics that induce a state of sedation, immobility, amnesia, and marked analgesia. Subjects may experience a strong feeling of… (More)

Topic mentions per year

Topic mentions per year

1976-2018
012319762018

Related topics

Related topics

15 relations

Narrower (8)

CI-581CalipsolKetamineKetamine Hydrochloride
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Broader (1)

General anesthetic drugs
In Bloodadministration & dosageaspects of radiation effectschemical synthesis
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Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Anesthetics, Dissociative
Ketamine
Phencyclidine
chemical synthesis
General anesthetic drugs
Ketamine Hydrochloride

Papers overview

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Highly Cited
2012
Highly Cited
2012
NMDA receptor and schizophrenia: a brief history.
Although glutamate was first hypothesized to be involved in the pathophysiology of schizophrenia in the 1980s, it was the… (More)
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2008
2008
Ketamine, but not phencyclidine, selectively modulates cerebellar GABA(A) receptors containing alpha6 and delta subunits.
Phencyclidine (PCP) and ketamine are dissociative anesthetics capable of inducing analgesia, psychomimetic behavior, and a… (More)
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2001
2001
Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth.
PURPOSE The goals of the study were to find a safe intraperitoneal injection anesthesia protocol for medium-duration surgery in… (More)
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2000
2000
Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine.
UNLABELLED Background The neuronal mechanisms responsible for dissociative anesthesia remain controversial. N-methyl-D-aspartate… (More)
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1991
1991
A rapid method for evaluating the behavioral effects of phencyclidine-like dissociative anesthetics in mice
A simple and rapid method for detecting the behavioral effects of phencyclidine and related dissociative anesthetics is described… (More)
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1988
1988
The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures.
Excitatory amino acid receptors in the mammalian central nervous system (CNS) are divided into 3 receptor subtypes: kainate… (More)
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Highly Cited
1986
Highly Cited
1986
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.
The compound MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine maleate)] is a potent anticonvulsant that… (More)
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1985
1985
Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid.
Excitatory amino acids depolarize central mammalian neurons by increasing membrane conductance. This increase in conductance can… (More)
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1983
1983
Patient acceptance of dissociative anesthetics.
A prospective study was undertaken to evaluate the efficacy, safety, and patient acceptance of low-dose ketamine when used to… (More)
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1980
1980
Use of dissociative anesthetics for the immobilization of captive bears: blood gas, hematology and biochemistry values.
Nineteen bears, representing five species (Helarctos malayanus, Ursus americanus, Ursus arctos, Tremarctos ornatus, Melursus… (More)
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