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Ketamine Hydrochloride

Known as: Ketamine HCl, Ketamine Hydrochloride [Chemical/Ingredient] 
The hydrochloride salt of a synthetic derivative of cyclohexanone with analgesic and anesthetic activities. Although its mechanism of action is not… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (2)

Anesthetics, DissociativeKetamine
AneurysmAngina PectorisCongestive heart failureDrug Allergy

Narrower (2)

CI-581Ketalar

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery
PurposeMajor spine surgery with multilevel instrumentation is followed by large amount of opioid consumption, significant pain… 
Highly Cited
2008
Highly Cited
2008
Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study.
CONTEXT Ketamine evokes psychosislike symptoms, and its primary action is to impair N-methyl-D-aspartate glutamate receptor… 
Highly Cited
2008
Highly Cited
2008
Small Molecule Disruption of G Protein βγ Subunit Signaling Inhibits Neutrophil Chemotaxis and Inflammation
G protein βγ subunit-dependent signaling is important for chemoattractant-dependent leukocyte chemotaxis. Selective small… 
Highly Cited
2005
Highly Cited
2005
S-Ketamine Anesthesia Increases Cerebral Blood Flow in Excess of the Metabolic Needs in Humans
Background:Animal studies have demonstrated neuroprotective properties of S-ketamine, but its effects on cerebral blood flow (CBF… 
Highly Cited
2003
Highly Cited
2003
Short-term infusion of the μ-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal
Highly Cited
2003
Highly Cited
2003
Differential Modulation of Remifentanil-induced Analgesia and Postinfusion Hyperalgesia by S-Ketamine and Clonidine in Humans
Background Experimental studies and clinical observations suggest a possible role for opioids to induce pain and hyperalgesia on… 
Highly Cited
2001
Highly Cited
2001
Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier
The contribution of organic anion transporters to the total efflux of 17beta-estradiol-D-17beta-glucuronide (E(2)17betaG) through… 
Highly Cited
1999
Highly Cited
1999
Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.
The present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (DA… 
Highly Cited
1992
Highly Cited
1992
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Highly Cited
1976
Highly Cited
1976
Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section
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