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Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats
- H. Kompagne, G. Bárdos, G. Szénási, I. Gacsályi, G. Lévay
- Psychology, Medicine
- Behavioural Brain Research
- 21 November 2008
A 3-week chronic mild stress (CMS) protocol decreased sucrose preference of rats and increased immobility in the forced swim test. It also induced social avoidance and increased grooming, but acted… Expand
The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study
- L. Hársing, I. Gacsályi, G. Szabó, E. Schmidt, G. Lévay
- Chemistry, Medicine
- Pharmacology Biochemistry and Behavior
- 1 March 2003
The in vitro and in vivo pharmacology of two glycine transporter-1 (GlyT1) inhibitors, N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)-propyl]sarcosine (NFPS) and… Expand
Properties of activated carbon controlling 2-Methylisoborneol adsorption
2-Methylisoborneol (MIB) is one of the most common taste and odour molecules found in water supplies. The use of activated carbons is known to be effective in removing MIB from water. In this work,… Expand
Detection of DNA adducts in HL-60 cells treated with hydroquinone and p-benzoquinone by 32P-postlabeling.
We have examined DNA adduct formation and cytotoxicity in HL-60 cells treated with either hydroquinone (HQ) or p-benzoquinone (p-BQ). Treatment of HL-60 cells with either HQ or p-BQ produced the same… Expand
Investigation of the DNA adducts formed in B6C3F1 mice treated with benzene: implications for molecular dosimetry.
- W. Bodell, D. N. Pathak, G. Lévay, Q. Ye, K. Pongracz
- Chemistry, Medicine
- Environmental health perspectives
- 1 December 1996
We have investigated the formation of DNA adducts in the bone marrow and white blood cells of male B6C3F1 mice treated with benzene using P1-enhanced 32P-postlabeling. No adducts were detected in the… Expand
Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy
Recent studies have provided evidence that activation of 5-HT1A receptors increases epileptic activity in the WAG/Rij rat model of absence epilepsy, and additional data have suggested the involvement… Expand
Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: Effects of GYKI 52466 and its novel analogues
RationaleAlthough emerging number of data supports the role of glutamate receptors and the potential of their antagonists in anxiety disorders, the involvement of… Expand
A Simplified Method for Estimation of Jarosite and Acid-Forming Sulfates in Acid Mine Wastes
mCPP-induced anxiety in the light-dark box in rats – a new method for screening anxiolytic activity
Abstract The activity of anxiolytic and other drugs in a light-dark test situation was studied in rats treated with the anxiogenic compound m-chlorophenyl-piperazine (mCPP). mCPP 0.5 mg/kg… Expand
Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils.
Excessive stimulation of N-methyl-D-aspartate (NMDA) receptors during ischemia contributes to apoptotic and excitotoxic nerve cell death. Kynurenic acid is a selective antagonist at the glycine… Expand