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PSMB5 protein, human

Known as: PSX Large Multifunctional Protease X, Proteasome Epsilon Chain, Multicatalytic Endopeptidase Complex Epsilon Chain 
Proteasome subunit beta type-5 (263 aa, ~28 kDa) is encoded by the human PSMB5 gene. This protein plays a role in proteasomal protein degradation.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The Parkinson's-associated protein, DJ-1, is a highly conserved homodimer, ubiquitously expressed in cells. Here we demonstrate… 
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Review
2014
Review
2014
For many years, the ubiquitin-26S proteasome degradation pathway was considered the primary route for proteasomal degradation… 
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Highly Cited
2013
Highly Cited
2013
SUMMARY In mammalian cells, hydrogen peroxide (H2O2)-induced adaptation to oxidative stress is strongly dependent on an Nrf2… 
Highly Cited
2010
Highly Cited
2010
Oxidized cytoplasmic and nuclear proteins are normally degraded by the proteasome, but accumulate with age and disease. We… 
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Highly Cited
2008
Highly Cited
2008
Substrates enter the cylindrical 20S proteasome through a gated channel that is regulated by the ATPases in the 19S regulatory… 
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Highly Cited
2008
Highly Cited
2008
The proteasome is the central regulatory protease of eukaryotic cells. Heteroheptameric α-subunit and β-subunit rings stack to… 
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Highly Cited
2005
Highly Cited
2005
The archaeal ATPase complex PAN, the homolog of the eukaryotic 26S proteasome-regulatory ATPases, was shown to associate… 
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Highly Cited
1999
Highly Cited
1999
Recent studies suggest that sepsis stimulates ubiquitin-dependent protein breakdown in skeletal muscle. In this proteolytic… 
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Highly Cited
1997
Highly Cited
1997
In human 20S proteasomes two copies of each of seven different alpha-type and seven different beta-type subunits are assembled to… 
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Highly Cited
1996
Highly Cited
1996
The eukaryotic 20S proteasome is responsible for the degradation of many cellular proteins, but how it is assembled and how its… 
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