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PSMB5 protein, human

Known as: PSX Large Multifunctional Protease X, Proteasome Epsilon Chain, Multicatalytic Endopeptidase Complex Epsilon Chain 
Proteasome subunit beta type-5 (263 aa, ~28 kDa) is encoded by the human PSMB5 gene. This protein plays a role in proteasomal protein degradation.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The Parkinson's-associated protein, DJ-1, is a highly conserved homodimer, ubiquitously expressed in cells. Here we demonstrate… Expand
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Review
2014
Review
2014
For many years, the ubiquitin-26S proteasome degradation pathway was considered the primary route for proteasomal degradation… Expand
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Highly Cited
2010
Highly Cited
2010
Oxidized cytoplasmic and nuclear proteins are normally degraded by the proteasome, but accumulate with age and disease. We… Expand
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Highly Cited
2008
Highly Cited
2008
Substrates enter the cylindrical 20S proteasome through a gated channel that is regulated by the ATPases in the 19S regulatory… Expand
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Highly Cited
2008
Highly Cited
2008
The proteasome is the central regulatory protease of eukaryotic cells. Heteroheptameric α-subunit and β-subunit rings stack to… Expand
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Highly Cited
2005
Highly Cited
2005
The archaeal ATPase complex PAN, the homolog of the eukaryotic 26S proteasome-regulatory ATPases, was shown to associate… Expand
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Highly Cited
2000
Highly Cited
2000
Most of the non-lysosomal proteolysis that occurs in eukaryotic cells is performed by a nonspecific and abundant barrel-shaped… Expand
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Highly Cited
1999
Highly Cited
1999
Recent studies suggest that sepsis stimulates ubiquitin-dependent protein breakdown in skeletal muscle. In this proteolytic… Expand
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Highly Cited
1997
Highly Cited
1997
In human 20S proteasomes two copies of each of seven different alpha-type and seven different beta-type subunits are assembled to… Expand
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Highly Cited
1996
Highly Cited
1996
The eukaryotic 20S proteasome is responsible for the degradation of many cellular proteins, but how it is assembled and how its… Expand
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