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multicatalytic endopeptidase complex

Known as: Prosome, Proteinase, Multicatalytic, Macropain 
Proteolytic complexes, proteolytic core of the proteasome system, that degrade cytosolic and nuclear proteins are implicated in ATP dependent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Grain weight is one of the most important components of grain yield and is controlled by quantitative trait loci (QTLs) derived… Expand
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Highly Cited
2005
Highly Cited
2005
Peroxisome proliferator-activated receptor-γ (PPAR-γ) has essential roles in adipogenesis and glucose homeostasis, and is a… Expand
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Highly Cited
2002
Highly Cited
2002
Wnt regulation of beta-catenin degradation is essential for development and carcinogenesis. beta-catenin degradation is initiated… Expand
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Highly Cited
2001
Highly Cited
2001
Complexes of the heat shock protein gp96 and antigenic peptides are taken up by antigen-presenting cells and presented by MHC… Expand
Review
2000
Review
2000
  • R. Kopito
  • Trends in cell biology
  • 2000
  • Corpus ID: 24294639
Intracellular and extracellular accumulation of aggregated protein are linked to many diseases, including ageing-related… Expand
Highly Cited
2000
Highly Cited
2000
MHC class I molecules function to present peptides eight to ten residues long to the immune system. These peptides originate… Expand
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Review
1998
Review
1998
Proteasomes are major sites for protein degradation in eukaryotic cells. The recent identification of selective proteasome… Expand
Highly Cited
1997
Highly Cited
1997
β‐catenin is a central component of the cadherin cell adhesion complex and plays an essential role in the Wingless/Wnt signaling… Expand
Review
1996
Review
1996
The proteasome is an essential component of the ATP-dependent proteolytic pathway in eukaryotic cells and is responsible for the… Expand
Highly Cited
1994
Highly Cited
1994
Reagents that inhibit the ubiquitin-proteasome proteolytic pathway in cells have not been available. Peptide aldehydes that… Expand