multicatalytic endopeptidase complex

Known as: Prosome, Proteinase, Multicatalytic, Macropain 
Proteolytic complexes, proteolytic core of the proteasome system, that degrade cytosolic and nuclear proteins are implicated in ATP dependent… (More)

Topic mentions per year

Topic mentions per year

1981-2017
05010019812017

Papers overview

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Highly Cited
2007
Highly Cited
2007
Grain weight is one of the most important components of grain yield and is controlled by quantitative trait loci (QTLs) derived… (More)
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Highly Cited
2003
Highly Cited
2003
Using L929 cells, we quantitated the macroeconomics of protein synthesis and degradation and the microeconomics of producing MHC… (More)
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Highly Cited
2002
Highly Cited
2002
The 26S proteasome mediates degradation of ubiquitin-conjugated proteins. Although ubiquitin is recycled from proteasome… (More)
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Highly Cited
2002
Highly Cited
2002
We have identified proteins that are abundant in affinity-purified proteasomes, but absent from proteasomes as previously defined… (More)
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Highly Cited
2002
Highly Cited
2002
Endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) appears to be specialized to produce peptides presented on class I major… (More)
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Highly Cited
2000
Highly Cited
2000
MHC class I molecules function to present peptides eight to ten residues long to the immune system. These peptides originate… (More)
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Highly Cited
2000
Highly Cited
2000
To determine why proteasome inhibitors prevent thymocyte death, we examined whether proteasomes degrade anti-apoptotic molecules… (More)
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Highly Cited
1998
Highly Cited
1998
The MDM2 oncoprotein targets the p53 tumor suppressor protein for degradation when the two proteins are expressed in cells. The… (More)
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Highly Cited
1995
Highly Cited
1995
Cytotoxic T lymphocytes lyse target cells after T-cell-receptor-mediated recognition of class I major histocompatibility complex… (More)
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Highly Cited
1994
Highly Cited
1994
Reagents that inhibit the ubiquitin-proteasome proteolytic pathway in cells have not been available. Peptide aldehydes that… (More)
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