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multicatalytic endopeptidase complex

Known as: Prosome, Proteinase, Multicatalytic, Macropain 
Proteolytic complexes, proteolytic core of the proteasome system, that degrade cytosolic and nuclear proteins are implicated in ATP dependent… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Most individuals with cystic fibrosis (CF) carry one or two mutations that result in a maturation defect of the full-length CFTR… 
Highly Cited
2003
Highly Cited
2003
ABSTRACT During the early stages of herpes simplex virus type 1 (HSV-1) infection, viral immediate-early regulatory protein ICP0… 
Review
2001
Review
2001
Abstract: Aging is characterized by accumulation of potentially harmful altered proteins that could lead to gradual deterioration… 
Highly Cited
1997
Highly Cited
1997
The proteasome is believed to participate in the generation of a large percentage of peptide ligands for MHC class I molecules… 
Highly Cited
1995
Highly Cited
1995
Proteasomes degrade endogenous proteins in the cytosol. The potential contribution of the proteasome to the effect of flanking… 
Highly Cited
1994
Highly Cited
1994
LMP2 and LMP7 are proteins encoded by MHC genes that are tightly linked to the genes encoding TAP, the transporter that conveys… 
Review
1993
Review
1993
The 26S proteasome is the central protease of the ubiquitin-dependent pathway of protein degradation and has a highly conserved…