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multicatalytic endopeptidase complex
Known as:
Prosome
, Proteinase, Multicatalytic
, Macropain
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Proteolytic complexes, proteolytic core of the proteasome system, that degrade cytosolic and nuclear proteins are implicated in ATP dependent…
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National Institutes of Health
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Related topics
Related topics
41 relations
20S core proteasome complex location
Cell Nucleus
In Blood
Multicatalytic proteinase (complex) activity
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Narrower (18)
26S proteasome
26S proteasome non-ATPase regulatory subunit 13
Ki antigen
LMP7 protein
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Broader (1)
Cytoplasm
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins.
Jerry M. Wright
,
P. Zeitlin
,
L. Cebotaru
,
S. Guggino
,
W. Guggino
Physiological Genomics
2004
Corpus ID: 22504506
Most individuals with cystic fibrosis (CF) carry one or two mutations that result in a maturation defect of the full-length CFTR…
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Highly Cited
2003
Highly Cited
2003
PML Residue Lysine 160 Is Required for the Degradation of PML Induced by Herpes Simplex Virus Type 1 Regulatory Protein ICP0
Chris Boutell
,
A. Orr
,
R. Everett
Journal of Virology
2003
Corpus ID: 6593493
ABSTRACT During the early stages of herpes simplex virus type 1 (HSV-1) infection, viral immediate-early regulatory protein ICP0…
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Review
2001
Review
2001
Implications of Protein Degradation in Aging
S. Goto
,
R. Takahashi
,
+4 authors
Ryoichi Abe
Annals of the New York Academy of Sciences
2001
Corpus ID: 34448432
Abstract: Aging is characterized by accumulation of potentially harmful altered proteins that could lead to gradual deterioration…
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Highly Cited
1997
Highly Cited
1997
The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing?
A. Vinitsky
,
L. C. Antón
,
H. L. Snyder
,
M. Orłowski
,
J. Bennink
,
J. Yewdell
Journal of Immunology
1997
Corpus ID: 25556634
The proteasome is believed to participate in the generation of a large percentage of peptide ligands for MHC class I molecules…
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Highly Cited
1997
Highly Cited
1997
Dissecting the assembly pathway of the 20S proteasome
Frank Zühl
,
E. Seemüller
,
R. Golbik
,
W. Baumeister
FEBS Letters
1997
Corpus ID: 46122226
Highly Cited
1995
Highly Cited
1995
The cleavage preference of the proteasome governs the yield of antigenic peptides
M. Eggers
,
Bettina Boes-Fabian
,
T. Ruppert
,
P. Kloetzel
,
Ulrich H. Koszinowski
Journal of Experimental Medicine
1995
Corpus ID: 5770500
Proteasomes degrade endogenous proteins in the cytosol. The potential contribution of the proteasome to the effect of flanking…
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Highly Cited
1994
Highly Cited
1994
MHC-encoded proteasome subunits LMP2 and LMP7 are not required for efficient antigen presentation.
J. Yewdell
,
Cheryl Lapham
,
I. Bačík
,
Thomas Spies
,
J. Bennink
Journal of Immunology
1994
Corpus ID: 23137128
LMP2 and LMP7 are proteins encoded by MHC genes that are tightly linked to the genes encoding TAP, the transporter that conveys…
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Review
1993
Review
1993
Structural features of 26S and 20S proteasomes.
A. Lupas
,
Abraham J. Koster
,
Wolfgang Baumeister
Enzyme and Protein
1993
Corpus ID: 43645144
The 26S proteasome is the central protease of the ubiquitin-dependent pathway of protein degradation and has a highly conserved…
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Highly Cited
1992
Highly Cited
1992
Alternative exon usage and processing of the major histocompatibility complex-encoded proteasome subunits.
Klaus Früh
,
Young Yang
,
+5 authors
Per A. Peterson
Journal of Biological Chemistry
1992
Corpus ID: 7953366
Highly Cited
1988
Highly Cited
1988
Electron microscopy and image analysis of the multicatalytic proteinase
W. Baumeister
,
B. Dahlmann
,
R. Hegerl
,
F. Kopp
,
L. Kuehn
,
G. Pfeifer
FEBS Letters
1988
Corpus ID: 23289779
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