26S proteasome

Known as: 26 S proteasome complex, 26S ATP-Dependent Protease, 26S Proteosome 
Proteasomes are large multicatalytic proteolytic complexes found in all eukaryotic cells, and simpler forms have been found in archaebacteria and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
0102019892018

Papers overview

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2012
2012
Accumulating evidence shows that proper degradation of proteins that affect defense responses in a positive or negative manner is… (More)
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Highly Cited
2010
Highly Cited
2010
Proteasomal dysfunction may play a role in neurodegenerative conditions and protein aggregation. Overexpression in neuronal cells… (More)
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Highly Cited
2008
Highly Cited
2008
We determined composition and relative roles of deubiquitylating proteins associated with the 26S proteasome in mammalian cells… (More)
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2007
2007
The 26S proteasome has a direct impact on cellular transcription regulation, cell-cycle progression, oncogenesis and apoptosis… (More)
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Highly Cited
2006
Highly Cited
2006
The 26S proteasome degrades polyubiquitinated proteins by an energy-dependent mechanism. Here we define multiple roles for ATP in… (More)
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Highly Cited
2003
Highly Cited
2003
Hsp90 has a diverse array of cellular roles including protein folding, stress response and signal transduction. Herein we report… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclin D1 is a proto-oncogene that is overexpressed in many cancers including breast and prostate. It plays a role in cell… (More)
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Highly Cited
2001
Highly Cited
2001
The ubiquitin-proteasome proteolytic pathway is pivotal in most biological processes. Despite a great level of information… (More)
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2001
2001
We investigated whether the assembly/disassembly of the 26S proteasome is regulated by phosphorylation/dephosphorylation. The… (More)
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1996
1996
In a search for regulatory proteins that interact with the leucine zipper motif of c-Fos in the yeast two-hybrid screen, we have… (More)
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