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Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing
The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six related minichromosome maintenance proteins (Mcm2-7) intoExpand
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3D map of the plant photosystem II supercomplex obtained by cryoelectron microscopy and single particle analysis
Here we describe the first 3D structure of the photosystem II (PSII) supercomplex of higher plants, constructed by single particle analysis of images obtained by cryoelectron microscopy. This largeExpand
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Structural basis for a reciprocal regulation between SCF and CSN.
Skp1-Cul1-Fbox (SCF) E3 ligases are activated by ligation to the ubiquitin-like protein Nedd8, which is reversed by the deneddylating Cop9 signalosome (CSN). However, CSN also promotes SCF substrateExpand
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Consequences of shoot density and stiffness for ecosystem engineering by benthic macrophytes in flow dominated areas: a hydrodynamic flume study
Within intertidal areas of European Atlantic coasts the distribution of the small seagrass Zostera noltii and the halophyte Spartina anglica can partially overlap, despite numerous bio- mechanical,Expand
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Structural basis for the subunit assembly of the anaphase-promoting complex
The anaphase-promoting complex or cyclosome (APC/C) is an unusually large E3 ubiquitin ligase responsible for regulating defined cell cycle transitions. Information on how its 13 constituent proteinsExpand
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Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor
The ubiquitylation of cell-cycle regulatory proteins by the large multimeric anaphase-promoting complex (APC/C) controls sister chromatid segregation and the exit from mitosis. Selection of APC/CExpand
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Corrigendum: Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout
Corrigendum: Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout
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Three-dimensional structure of the plant photosystem II reaction centre at 8 Å resolution
Photosystem II is a multisubunit enzyme complex involved in plant photosynthesis. It uses solar energy to catalyse the breakdown of water to reducing equivalents and molecular oxygen. NativeExpand
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Origin Licensing Requires ATP Binding and Hydrolysis by the MCM Replicative Helicase
Summary Loading of the six related Minichromosome Maintenance (MCM) proteins as head-to-head double hexamers during DNA replication origin licensing is crucial for ensuring once-per-cell-cycle DNAExpand
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Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication
Eukaryotic DNA replication initiates from multiple replication origins. To ensure each origin fires just once per cell cycle, initiation is divided into two biochemically discrete steps: the Mcm2‐7Expand
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