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PRKDC protein, human

Known as: DNA-PKcs, DNA- PKcs protein, human, DNAPK protein, human 
DNA-dependent protein kinase catalytic subunit (4128 aa, ~469 kDa) is encoded by the human PRKDC gene. This protein is involved in both DNA damage… 
National Institutes of Health

Related topics

Related topics

22 relations
CDK10 protein, humanCell CycleDNA RepairDNA Repair Gene

Broader (2)

DNA-dependent protein kinaseNuclear Proteins

Papers overview

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Highly Cited
2002
Highly Cited
2002
Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein.
The DNA-dependent protein kinase (DNA-PK) complex, which is composed of a DNA-dependent kinase subunit (DNA-PKcs) and the Ku70/80… 
Highly Cited
2002
Highly Cited
2002
Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellites.
Human colorectal, endometrial, and gastric cancers with defective DNA mismatch repair (MMR) have microsatellite instability, a… 
2002
2002
Spectroscopic characterization of the NO adduct of hydroxylamine oxidoreductase.
Hydroxylamine oxidoreductase (HAO) from the autotrophic nitrifying bacterium Nitrosomonas europaea catalyzes the oxidation of… 
1998
1998
Failure of Hairpin-Ended and Nicked DNA To Activate DNA-Dependent Protein Kinase: Implications for V(D)J Recombination
ABSTRACT V(D)J recombination is initiated by a coordinated cleavage reaction that nicks DNA at two sites and then forms a hairpin… 
1998
1998
High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro.
The DNA-dependent protein kinase (DNA-PK) holoenzyme consists of a 470-kDa catalytic subunit (DNA-PKcs), a DNA-binding regulatory… 
1997
1997
The DNA-dependent protein kinase catalytic subunit (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells.
The DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase linked to DNA repair and V(D)J recombination. It is… 
1994
1994
The primary structure of cytochrome P460 of Nitrosomonas europaea: Presence of a c‐heme binding motif
1993
1993
Evidence for the structure of the active site heme P460 in hydroxylamine oxidoreductase of Nitrosomonas.
Hydroxylamine oxidoreductase (HAO) is responsible for the oxidation of hydroxylamine to nitrite in nitrification by Nitrosomonas… 
1988
1988
Effect of solvent, pressure and temperature on reaction rates of the multiheme hydroxylamine oxidoreductase. Evidence for conformational change.
Hydroxylamine oxidoreductase (HAO) of the ammonia-oxidizing bacterium Nitrosomonas catalyzes the oxidation: NH2OH + H2O----HNO2… 
Highly Cited
1969
Highly Cited
1969
Photosensitization of skin in vivo by furocoumarins (psoralens).
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