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CDK10 protein, human

Known as: cyclin-dependent kinase (CDC2-like) 10 protein, human, Serine/Threonine-Protein Kinase PISSLRE, PISSLRE Protein 
Cyclin-dependent kinase 10 (360 aa, ~41 kDa) is encoded by the human CDK10 gene. This protein plays a role in cell cycle regulation and protein… Expand
National Institutes of Health

Related topics

Related topics

26 relations
CDK10 geneCell Cycle ControlCell NucleusCell Proliferation
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Broader (2)

Cyclin-Dependent KinasesProtein-Serine-Threonine Kinases

Papers overview

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2015
2015
Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report
BackgroundCyclin-dependent kinase 10 (CDK10) has recently been identified as a tumor suppressor and, concordantly, its encoding… Expand
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2014
2014
G-protein αq participates in the steroid hormone 20-hydroxyecdysone nongenomic signal transduction
The nuclear receptor-mediated genomic pathways of the animal steroid hormones are well known. However, the cell membrane receptor… Expand
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2013
2013
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.
Cyclin-dependent kinases (CDKs) regulate a variety of fundamental cellular processes. CDK10 stands out as one of the last orphan… Expand
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2012
2012
CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells
Cyclin-dependent kinase 10 (CDK10) is a member of the Cdc2 family of kinases, and has been demonstrated to be an… Expand
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2012
2012
Proyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cells
Endocrine therapies that inhibit estrogen receptor (ER)-α signaling are the most common and effective treatment for ER-α-positive… Expand
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2009
2009
CDK10 is not a target for aberrant DNA methylation in breast cancer.
BACKGROUND Loss of cyclin-dependent kinase (CDK) 10 expression may be an important mechanism of tamoxifen resistance and the 5… Expand
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Highly Cited
2008
Highly Cited
2008
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
Therapies that target estrogen signaling have transformed the treatment of breast cancer. However, the effectiveness of these… Expand
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2006
2006
Identification of murine cdk10: association with Ets2 transcription factor and effects on the cell cycle.
Cyclin-dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best… Expand
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2006
2006
Proteomic analysis reveals novel molecules involved in insulin signaling pathway.
The binding of insulin to its receptor triggers a signaling cascade regulated by protein complexes via tyrosine phosphorylation… Expand
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2000
2000
Human CDK10 gene isoforms.
The CDK10/PISSLRE gene has been shown to encode two different CDK-like putative kinases. The function(s) of the gene products are… Expand
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