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CDK10 protein, human

Known as: cyclin-dependent kinase (CDC2-like) 10 protein, human, Serine/Threonine-Protein Kinase PISSLRE, PISSLRE Protein 
Cyclin-dependent kinase 10 (360 aa, ~41 kDa) is encoded by the human CDK10 gene. This protein plays a role in cell cycle regulation and protein… 
National Institutes of Health

Related topics

Related topics

26 relations
CDK10 geneCell Cycle ControlCell NucleusCell Proliferation

Broader (2)

Cyclin-Dependent KinasesProtein-Serine-Threonine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness
The primary cilium is a key organelle in numerous physiological and developmental processes. Genetic defects in the formation of… 
2018
2018
Downregulated CDK10 expression in gastric cancer: Association with tumor progression and poor prognosis.
The tumor suppressor characteristics of cyclin‑dependent kinase 10 (CDK10) in nasopharyngeal carcinoma and breast cancer have… 
Review
2017
Review
2017
The awakening of the CDK10/Cyclin M protein kinase
Cyclin-dependent kinases (CDKs) play important roles in the control of fundamental cellular processes. Some of the most… 
2014
2014
In a nongenomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription.
The insect steroid hormone 20-hydroxyecdysone (20E) regulates gene transcription via a genomic pathway by forming a transcription… 
Highly Cited
2013
Highly Cited
2013
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome
Significance STAR syndrome is an X-linked dominant developmental disorder caused by mutations in FAM58A, which codes for an… 
2011
2011
CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells
Cyclin-dependent kinase 10 (CDK10) is a member of the Cdc2 family of kinases, and has been demonstrated to be an important… 
2009
2009
Identification of nuclear structural protein alterations associated with seminomas
Currently, there are no specific markers available for the early detection and for monitoring testicular cancer. Based upon an… 
Highly Cited
2008
Highly Cited
2008
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
2006
2006
Identification of murine cdk10: Association with Ets2 transcription factor and effects on the cell cycle
Cyclin‐dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best… 
2000
2000
Human CDK10 gene isoforms.
The CDK10/PISSLRE gene has been shown to encode two different CDK-like putative kinases. The function(s) of the gene products are… 
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