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CDK10 protein, human

Known as: cyclin-dependent kinase (CDC2-like) 10 protein, human, Serine/Threonine-Protein Kinase PISSLRE, PISSLRE Protein 
Cyclin-dependent kinase 10 (360 aa, ~41 kDa) is encoded by the human CDK10 gene. This protein plays a role in cell cycle regulation and protein… Expand
National Institutes of Health

Related topics

Related topics

26 relations
CDK10 geneCell Cycle ControlCell NucleusCell Proliferation
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Broader (2)

Cyclin-Dependent KinasesProtein-Serine-Threonine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report
BackgroundCyclin-dependent kinase 10 (CDK10) has recently been identified as a tumor suppressor and, concordantly, its encoding… Expand
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2014
2014
In a nongenomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription.
The insect steroid hormone 20-hydroxyecdysone (20E) regulates gene transcription via a genomic pathway by forming a transcription… Expand
2014
2014
G-protein αq participates in the steroid hormone 20-hydroxyecdysone nongenomic signal transduction
The nuclear receptor-mediated genomic pathways of the animal steroid hormones are well known. However, the cell membrane receptor… Expand
2013
2013
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome
Significance STAR syndrome is an X-linked dominant developmental disorder caused by mutations in FAM58A, which codes for an… Expand
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2012
2012
CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells
Cyclin-dependent kinase 10 (CDK10) is a member of the Cdc2 family of kinases, and has been demonstrated to be an important… Expand
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2009
2009
Identification of nuclear structural protein alterations associated with seminomas
Currently, there are no specific markers available for the early detection and for monitoring testicular cancer. Based upon an… Expand
Highly Cited
2008
Highly Cited
2008
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
Therapies that target estrogen signaling have transformed the treatment of breast cancer. However, the effectiveness of these… Expand
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2008
2008
Unraveling the complexity of endocrine resistance in breast cancer by functional genomics.
Despite the proven benefit of antiestrogen drugs in breast cancer treatment, resistant disease ultimately develops in advanced… Expand
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2006
2006
Identification of murine cdk10: Association with Ets2 transcription factor and effects on the cell cycle
Cyclin‐dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best… Expand
2000
2000
Human CDK10 gene isoforms.
The CDK10/PISSLRE gene has been shown to encode two different CDK-like putative kinases. The function(s) of the gene products are… Expand
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