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CDK10 protein, human
Known as:
cyclin-dependent kinase (CDC2-like) 10 protein, human
, Serine/Threonine-Protein Kinase PISSLRE
, PISSLRE Protein
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Cyclin-dependent kinase 10 (360 aa, ~41 kDa) is encoded by the human CDK10 gene. This protein plays a role in cell cycle regulation and protein…
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National Institutes of Health
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Related topics
Related topics
26 relations
CDK10 gene
Cell Cycle Control
Cell Nucleus
Cell Proliferation
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Broader (2)
Cyclin-Dependent Kinases
Protein-Serine-Threonine Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness
Vincent J Guen
,
S. Edvardson
,
+10 authors
O. Elpeleg
American Journal of Medical Genetics. Part A
2018
Corpus ID: 37952701
The primary cilium is a key organelle in numerous physiological and developmental processes. Genetic defects in the formation of…
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2018
2018
Downregulated CDK10 expression in gastric cancer: Association with tumor progression and poor prognosis.
Yanjie You
,
F. Bai
,
+4 authors
Ximei Li
Molecular Medicine Reports
2018
Corpus ID: 4640038
The tumor suppressor characteristics of cyclin‑dependent kinase 10 (CDK10) in nasopharyngeal carcinoma and breast cancer have…
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Review
2017
Review
2017
The awakening of the CDK10/Cyclin M protein kinase
Vincent J Guen
,
C. Gamble
,
J. Lees
,
P. Colas
OncoTarget
2017
Corpus ID: 1975956
Cyclin-dependent kinases (CDKs) play important roles in the control of fundamental cellular processes. Some of the most…
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2014
2014
In a nongenomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription.
Wen Liu
,
Mei-Juan Cai
,
Jin-Xing Wang
,
Xiao-Fan Zhao
Endocrinology
2014
Corpus ID: 24426092
The insect steroid hormone 20-hydroxyecdysone (20E) regulates gene transcription via a genomic pathway by forming a transcription…
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Highly Cited
2013
Highly Cited
2013
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome
Vincent J Guen
,
C. Gamble
,
+7 authors
P. Colas
Proceedings of the National Academy of Sciences
2013
Corpus ID: 31010840
Significance STAR syndrome is an X-linked dominant developmental disorder caused by mutations in FAM58A, which codes for an…
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2011
2011
CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells
J. Yu
,
X. Zhong
,
+5 authors
Yun-fu Cui
Oncology Report
2011
Corpus ID: 3229
Cyclin-dependent kinase 10 (CDK10) is a member of the Cdc2 family of kinases, and has been demonstrated to be an important…
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2009
2009
Identification of nuclear structural protein alterations associated with seminomas
E. S. Leman
,
A. Magheli
,
Koh Meng Aw Yong
,
G. Netto
,
S. Hinz
,
R. Getzenberg
Journal of Cellular Biochemistry
2009
Corpus ID: 33383067
Currently, there are no specific markers available for the early detection and for monitoring testicular cancer. Based upon an…
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Highly Cited
2008
Highly Cited
2008
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
E. Iorns
,
N. Turner
,
+7 authors
A. Ashworth
Cancer Cell
2008
Corpus ID: 24400497
2006
2006
Identification of murine cdk10: Association with Ets2 transcription factor and effects on the cell cycle
L. Bagella
,
C. Giacinti
,
C. Simone
,
A. Giordano
Journal of Cellular Biochemistry
2006
Corpus ID: 6466804
Cyclin‐dependent kinases (cdks) are the catalytic subunits of a large family of serine/threonine protein kinases whose best…
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2000
2000
Human CDK10 gene isoforms.
J. Sergere
,
J. Thuret
,
G. Le Roux
,
E. Carosella
,
F. Leteurtre
Biochemical and Biophysical Research…
2000
Corpus ID: 26737367
The CDK10/PISSLRE gene has been shown to encode two different CDK-like putative kinases. The function(s) of the gene products are…
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