DNA-dependent protein kinase

Known as: DNA Dependent Protein Serine Threonine Kinase, DNA-Dependent Protein Serine-Threonine Kinase, dna pk 
A serine-threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding protein substrates including the TUMOR SUPPRESSOR… (More)

Topic mentions per year

Topic mentions per year

1989-2018
020406019892018

Papers overview

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Highly Cited
2005
Highly Cited
2005
Ataxia-telangiectasia mutated (ATM), ataxia-telangiectasia and Rad3-related (ATR) and DNA-dependent protein kinase catalytic… (More)
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Highly Cited
2005
Highly Cited
2005
Ionizing radiation, but not stimulation with epidermal growth factor (EGF), triggers EGF receptor (EGFR) import into the nucleus… (More)
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Highly Cited
2004
Highly Cited
2004
Full activation of protein kinase B (PKB)/Akt requires phosphorylation on Thr-308 and Ser-473 by 3-phosphoinositide-dependent… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in the Artemis protein in humans result in hypersensitivity to DNA double-strand break-inducing agents and absence of B… (More)
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Highly Cited
2002
Highly Cited
2002
Nonhomologous end-joining (NHEJ) is the predominant pathway that repairs DNA double-strand breaks (DSBs) in mammalian cells. The… (More)
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Highly Cited
1999
Highly Cited
1999
UNLABELLED Replication protein A (RPA) is a DNA single-strand binding protein essential for DNA replication, recombination and… (More)
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Highly Cited
1999
Highly Cited
1999
Caffeine exposure sensitizes tumor cells to ionizing radiation and other genotoxic agents. The radiosensitizing effects of… (More)
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Highly Cited
1997
Highly Cited
1997
DNA-damaging agents signal to p53 through as yet unidentified posttranscriptional mechanisms. Here we show that phosphorylation… (More)
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Highly Cited
1993
Highly Cited
1993
The DNA-dependent protein kinase (DNA-PK) phosphorylates Sp1 and several other nuclear proteins. Here, we show that Sp1 and the… (More)
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Highly Cited
1990
Highly Cited
1990
Efficient transcription of SV40 early genes requires transcription factor Sp1. Here, we report that SV40 infection induces Sp1… (More)
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