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DNA Repair Gene

DNA Repair Genes encode DNA Repair Proteins, involved in enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage… 
National Institutes of Health

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A/G-Specific Adenine DNA GlycosylaseBABAM1 protein, humanBRCA1-A Complex Subunit AbraxasBRCA1-A Complex Subunit RAP80, human
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FANCA gene

Papers overview

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2019
2019
Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors
Importance Approximately 50% of the risk for the development of testicular germ cell tumors (TGCTs) is estimated to be heritable… 
2019
2019
Better screened than sorry!-an informed panel of inherited DNA repair gene variants for prostate cancer screening and prognostication.
DNA repair gene (DRG) alterations have been established as an emerging class of biomarkers and targets for cancer therapies… 
2018
2018
Inherited defects in checkpoint kinase 2 (CHEK2) to confer increased susceptibility to testicular germ cell tumors.
1515Background: Although up to 50% of testicular germ cell tumor (TGCT) risk is predicted to be inherited, no Mendelian TGCT… 
2018
2018
Abstract 424: Defining prostate cancer subtypes by genomic features associated with defects in DNA repair processes
Introduction: Prostate cancer (PC) exhibits a spectrum of genomic aberrations, a subset of which associate with responses to… 
Review
2016
Review
2016
Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes
At present, many publications have evaluated the correlation between the DNA repair gene polymorphisms and glioma susceptibility… 
2016
2016
Inherited mutations in DNA repair genes in men with metastatic castration-resistant prostate cancer.
5009Background: Inherited mutations in genes that regulate DNA repair processes such as BRCA1 and BRCA2 associate with increased… 
2015
2015
Effect of transporter and DNA repair gene polymorphisms to lung cancer chemotherapy toxicity
Lung cancer is the first leading cause of cancer deaths. Chemotherapy toxicity is one of factors that limited the efficacy of… 
Review
2015
Review
2015
DNA repair gene ERCC 1 polymorphisms and glioma susceptibility among Chinese population : a meta-analysis
Background: Excision repair cross complementation group 1 (ERCC1) has been shown to be involved in the progression of glioma… 
2014
2014
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma.
Aflatoxin B1 (AFB1) is an important environmental carcinogen and can induce DNA damage and involve in the carcinogenesis of… 
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