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DNA Repair Gene
DNA Repair Genes encode DNA Repair Proteins, involved in enzymatic restoration of DNA structure after chemical, radiation, or spontaneous damage…
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National Institutes of Health
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Related topics
Related topics
50 relations
A/G-Specific Adenine DNA Glycosylase
BABAM1 protein, human
BRCA1-A Complex Subunit Abraxas
BRCA1-A Complex Subunit RAP80, human
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FANCA gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors
S. AlDubayan
,
L. Pyle
,
+25 authors
D. Lessel
JAMA oncology
2019
Corpus ID: 59225973
Importance Approximately 50% of the risk for the development of testicular germ cell tumors (TGCTs) is estimated to be heritable…
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2019
2019
Better screened than sorry!-an informed panel of inherited DNA repair gene variants for prostate cancer screening and prognostication.
Giulia Fracassi
,
F. Lorenzin
,
F. Demichelis
Annals of translational medicine
2019
Corpus ID: 203638662
DNA repair gene (DRG) alterations have been established as an emerging class of biomarkers and targets for cancer therapies…
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2018
2018
Inherited defects in checkpoint kinase 2 (CHEK2) to confer increased susceptibility to testicular germ cell tumors.
S. AlDubayan
,
Louisa Pyle
,
+6 authors
D. Lessel
2018
Corpus ID: 80896194
1515Background: Although up to 50% of testicular germ cell tumor (TGCT) risk is predicted to be inherited, no Mendelian TGCT…
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2018
2018
Abstract 424: Defining prostate cancer subtypes by genomic features associated with defects in DNA repair processes
N. D. Sarkar
,
Emily A. Kohlbrenner
,
I. Coleman
,
P. Nelson
Molecular and Cellular Biology / Genetics
2018
Corpus ID: 80804167
Introduction: Prostate cancer (PC) exhibits a spectrum of genomic aberrations, a subset of which associate with responses to…
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Review
2016
Review
2016
Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes
Kun Liu
,
Yugang Jiang
Cellular and Molecular Neurobiology
2016
Corpus ID: 22657295
At present, many publications have evaluated the correlation between the DNA repair gene polymorphisms and glioma susceptibility…
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2016
2016
Inherited mutations in DNA repair genes in men with metastatic castration-resistant prostate cancer.
P. Nelson
,
J. Mateo
,
+17 authors
C. Pritchard
2016
Corpus ID: 80899053
5009Background: Inherited mutations in genes that regulate DNA repair processes such as BRCA1 and BRCA2 associate with increased…
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2015
2015
Effect of transporter and DNA repair gene polymorphisms to lung cancer chemotherapy toxicity
Juan Chen
,
Linlin Wu
,
+10 authors
Zhaoqian Liu
Tumor Biology
2015
Corpus ID: 23782108
Lung cancer is the first leading cause of cancer deaths. Chemotherapy toxicity is one of factors that limited the efficacy of…
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Review
2015
Review
2015
DNA repair gene ERCC 1 polymorphisms and glioma susceptibility among Chinese population : a meta-analysis
Chunming Jiang
,
Fang Shen
,
+4 authors
Xianmei Huang
2015
Corpus ID: 23440798
Background: Excision repair cross complementation group 1 (ERCC1) has been shown to be involved in the progression of glioma…
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2014
2014
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma.
Jin-Guang Yao
,
Xiao-Ying Huang
,
Xi-Dai Long
International journal of clinical and…
2014
Corpus ID: 10705808
Aflatoxin B1 (AFB1) is an important environmental carcinogen and can induce DNA damage and involve in the carcinogenesis of…
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