PRKDC gene

Known as: protein kinase, DNA-activated, catalytic polypeptide, DNA-PKcs, HYPERRADIOSENSITIVITY COMPLEMENTING 1, MOUSE, HOMOLOG OF 
This gene plays a role in cellular homeostasis by transcription modulation. The gene is also involved in V(D)J recombination.
National Institutes of Health

Papers overview

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2013
2013
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs; encoded by PRKDC) functions in DNA non-homologous end-joining (NHEJ… (More)
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2013
2013
When the integrity of the genome is threatened, cells activate a complex, kinase-based signaling network to arrest the cell cycle… (More)
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2012
2012
Artemis is an endonuclease that opens coding hairpin ends during V(D)J recombination and has critical roles in postirradiation… (More)
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Highly Cited
2011
Highly Cited
2011
Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal human premature ageing disease, characterized by premature… (More)
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2008
2008
Gene expression profiles were studied by microarray analysis in 2 sets of archival breast cancer tissues from patients with… (More)
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2001
2001
Anderson, C. W., Dunn, J. J., Freimuth, P. I., Galloway, A. M. and Allalunis-Turner, M. J. Frameshift Mutation in PRKDC, the Gene… (More)
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2000
2000
DNA-dependent protein kinase (DNA-PK) is utilized in both DNA double-strand break repair (DSBR) and V(D)J recombination, but the… (More)
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1998
1998
The catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) is a member of a sub-family of phosphatidylinositol (PI) 3… (More)
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1998
1998
A 30-kb genomic segment containing the promoter and first 9 exons of PRKDC, the gene encoding the catalytic subunit (DNA-PKcs) of… (More)
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1996
1996
Cognitive ERPs and EEG spectral differences were compared in three groups of children: nonreferred controls, those with a… (More)
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