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Non-Homologous DNA End-Joining

Known as: DNA End-Joining, Non-Homologous, End-Joining, Non-Homologous DNA, Non-Homologous End Joining 
Non-homologous DNA end joining (NHEJ) can only repair double-strand breaks in which two DNA ends are rejoined by DNA ligase at regions of little or… 
National Institutes of Health

Related topics

Related topics

25 relations
Cell SurvivalDCLRE1C geneDCLRE1C wt AlleleDouble-Strand Break Repair Protein MRE11A

Broader (1)

DNA End-Joining Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Touching base with PARPs: moonlighting in the repair of UV lesions and double-strand breaks.
Highly Cited
2012
Highly Cited
2012
Unwinding and Rewinding: Double Faces of Helicase?
Helicases are enzymes that use ATP-driven motor force to unwind double-stranded DNA or RNA. Recently, increasing evidence… 
Highly Cited
2010
Highly Cited
2010
ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells
We recently demonstrated that human embryonic stem cells (hESCs) utilize homologous recombination repair (HRR) as primary means… 
Highly Cited
2009
Highly Cited
2009
Significant association of ERCC6 single nucleotide polymorphisms with bladder cancer susceptibility in Taiwan.
AIM To evaluate the association between the polymorphisms of the ERCC6 DNA repair gene, which plays an important role in… 
Review
2009
Review
2009
Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage.
Highly Cited
2007
Highly Cited
2007
Long-term XPC silencing reduces DNA double-strand break repair.
To study the relationships between different DNA repair pathways, we established a set of clones in which one specific DNA repair… 
Review
2006
Review
2006
Epidermal growth factor receptor and DNA double strand break repair: the cell's self-defence.
Review
2003
Review
2003
Non-homologous DNA end joining.
DNA double-strand breaks (DSBs) are a serious threat for the cell and when not repaired or misrepaired can result in mutations or… 
2001
2001
The role of DNA polymerase activity in human non-homologous end joining.
In mammalian cells, DNA double-strand breaks are repaired mainly by non-homologous end joining, which modifies and ligates two… 
Highly Cited
1994
Highly Cited
1994
Mechanisms of overlap formation in nonhomologous DNA end joining
Rejoining of nonhomologous DNA termini plays a central role in processes of illegitimate recombination. In Xenopus egg extracts… 
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