Non-Homologous DNA End-Joining

Known as: DNA End-Joining, Non-Homologous, End-Joining, Non-Homologous DNA, Non-Homologous End Joining 
Non-homologous DNA end joining (NHEJ) can only repair double-strand breaks in which two DNA ends are rejoined by DNA ligase at regions of little or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
010020019962018

Papers overview

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Review
2016
Review
2016
DNA double-strand breaks (DSBs), which arise following exposure to a number of endogenous and exogenous agents, can be repaired… (More)
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Highly Cited
2009
Highly Cited
2009
The mammalian Mre11–Rad50–Nbs1 (MRN) complex coordinates double-strand break signaling with repair by homologous recombination… (More)
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Highly Cited
2008
Highly Cited
2008
Double-strand breaks activate the ataxia telangiectasia mutated (ATM) kinase, which promotes the accumulation of DNA damage… (More)
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Highly Cited
2007
Highly Cited
2007
Immunoglobulin variable region exons are assembled in developing B cells by V(D)J recombination. Once mature, these cells undergo… (More)
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2002
2002
Recent evidence suggests that DNA double strand breaks (DSBs) are introduced in neurons during the course of normal development… (More)
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2002
2002
BS is an inherited cancer predisposition disorder caused by inactivation of the RecQ family helicase, BLM. One of the defining… (More)
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Highly Cited
2001
Highly Cited
2001
Early after infection, the retroviral RNA genome is reverse transcribed to generate a linear cDNA copy, then that copy is… (More)
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Highly Cited
2001
Highly Cited
2001
DNA double strand break (DSB) repair by non-homologous end joining (NHEJ) in mammalian cells requires the Ku70-Ku80 heterodimer… (More)
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Highly Cited
1998
Highly Cited
1998
Eukaryotic cells repair DNA double-strand breaks (DSBs) by at least two pathways, homologous recombination (HR) and non… (More)
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Highly Cited
1997
Highly Cited
1997
The discovery of homologues from the yeast Saccharomyces cerevisiae of the human Ku DNA-end-binding proteins (HDF1 and KU80) has… (More)
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