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Non-Homologous DNA End-Joining

Known as: DNA End-Joining, Non-Homologous, End-Joining, Non-Homologous DNA, Non-Homologous End Joining 
Non-homologous DNA end joining (NHEJ) can only repair double-strand breaks in which two DNA ends are rejoined by DNA ligase at regions of little or… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
DNA double-strand breaks (DSBs) are the most dangerous type of DNA damage because they can result in the loss of large… Expand
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Review
2017
Review
2017
A DNA double-strand break (DSB) is considered to be a critical DNA lesion because its misrepair can cause severe mutations, such… Expand
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Review
2017
Review
2017
Genome editing promises giant leaps forward in advancing biotechnology, agriculture, and basic research. The process relies on… Expand
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Review
2017
Review
2017
With its variety of applications, the CRISPR/Cas9 genome editing technology has been rapidly evolving in the last few years. In… Expand
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Review
2017
Review
2017
Targeted genome editing has become a powerful genetic tool for studying gene function or for modifying genomes by correcting… Expand
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Review
2017
Review
2017
The emergence of sequence-specific nucleases that enable genome editing is revolutionizing basic and applied biology. Since the… Expand
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Review
2017
Review
2017
The global agricultural landscape regarding the commercial cultivation of genetically modified (GM) crops is mosaic. Meanwhile, a… Expand
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Review
2010
Review
2010
Double-strand DNA breaks are common events in eukaryotic cells, and there are two major pathways for repairing them: homologous… Expand
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Review
2003
Review
2003
Non-homologous DNA end-joining (NHEJ) — the main pathway for repairing double-stranded DNA breaks — functions throughout the cell… Expand
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Highly Cited
1998
Highly Cited
1998
Eukaryotic cells repair DNA double-strand breaks (DSBs) by at least two pathways, homologous recombination (HR) and non… Expand
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