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PPIase activity

Known as: peptidylprolyl cis-trans isomerase activity, peptidylproline cis-trans-isomerase activity, peptidylprolyl isomerase activity 
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). [EC:5.2.1.8]
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
We demonstrate that the transition from a reliance on glycolysis to oxidative phosphorylation in a transformed cell line is… Expand
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Highly Cited
2010
Highly Cited
2010
The proteomes expressed at 4°C and 18°C by the psychrophilic Antarctic bacterium Pseudoalteromonas haloplanktis have been… Expand
Highly Cited
2010
Highly Cited
2010
The neuronal protein α-synuclein (α-syn) plays a central role in Parkinson's disease (PD). The pathological features of PD are… Expand
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Highly Cited
2003
Highly Cited
2003
Chloroplast cyclophilin has been identified as a potential candidate of enzymes in chloroplasts that are regulated by thioredoxin… Expand
Review
2002
Review
2002
Mitochondria play a critical role in initiating both apoptotic and necrotic cell death. A major player in this process is the… Expand
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Highly Cited
1994
Highly Cited
1994
Binding of mitochondrial matrix cyclophilin (CyP) to the rat liver mitochondrial membranes was detected by SDS/PAGE and Western… Expand
Highly Cited
1994
Highly Cited
1994
In addition to their application in organ transplantation, immunosuppressive drugs are valuable tools for studying signal… Expand
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Highly Cited
1990
Highly Cited
1990
Proliferation and immunologic function of T lymphocytes are initiated by signals from the antigen receptor that are inhibited by… Expand
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Highly Cited
1990
Highly Cited
1990
The immunosuppressants FK506 and rapamycin bind to the same immunophilin, FK506 binding protein (FKBP), and inhibit distinct… Expand
Highly Cited
1990
Highly Cited
1990
We have recently isolated an abundant cytosolic protein from human T-cells which specifically binds the immunosuppressive agent… Expand
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