Cyclophilins

Known as: Cyclophilin, Cyclophilins [Chemical/Ingredient], Cyclosporin-Binding Proteins 
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Following attachment to primary receptor heparan sulfate proteoglycans (HSPG), human papillomavirus type 16 (HPV16) particles… (More)
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Review
2005
Review
2005
Cyclophilins (Enzyme Commission (EC) number 5.1.2.8) belong to a group of proteins that have peptidyl-prolyl cis-trans isomerase… (More)
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Highly Cited
2005
Highly Cited
2005
The main regulators of leukocyte trafficking during inflammatory responses are chemokines. However, another class of recently… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Cyclosporin A specifically suppresses hepatitis C virus (HCV) replication in vitro at clinically achievable… (More)
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Highly Cited
1997
Highly Cited
1997
The cyclophilins and FK506 binding proteins (FKBPs) bind to cyclosporin A, FK506, and rapamycin and mediate their… (More)
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Highly Cited
1996
Highly Cited
1996
The HIV-1 capsid protein forms the conical core structure at the center of the mature virion. Capsid also binds the human… (More)
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Highly Cited
1994
Highly Cited
1994
CYCLOPHILINS are a family of proteins that bind the immunosuppressant cyclosporin A, possess peptidyl–prolylcis–trans isomerase… (More)
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Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… (More)
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Highly Cited
1989
Highly Cited
1989
The enzyme peptidyl-prolyl cis-trans isomerase (PPIase) was recently discovered in mammalian tissues and purified from porcine… (More)
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Highly Cited
1984
Highly Cited
1984
Cyclophilin, a specific cytosolic binding protein responsible for the concentration of the immunosuppressant cyclosporin A by… (More)
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