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Cyclophilins

Known as: Cyclophilin, Cyclophilins [Chemical/Ingredient], Cyclosporin-Binding Proteins 
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological… Expand
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Review
2005
Review
2005
SummaryCyclophilins (Enzyme Commission (EC) number 5.1.2.8) belong to a group of proteins that have peptidyl-prolyl cis-trans… Expand
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Highly Cited
1996
Highly Cited
1996
The HIV-1 capsid protein forms the conical core structure at the center of the mature virion. Capsid also binds the human… Expand
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Highly Cited
1994
Highly Cited
1994
CYCLOPHILINS are a family of proteins that bind the immunosuppressant cyclosporin A, possess peptidyl–prolylcis–trans isomerase… Expand
Highly Cited
1992
Highly Cited
1992
We have isolated an 18-kDa peptide (designated sp18, for 18-kDa secreted protein) from the conditioned medium of… Expand
Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… Expand
Highly Cited
1989
Highly Cited
1989
The enzyme peptidyl-prolyl cis-trans isomerase (PPIase) was recently discovered in mammalian tissues and purified from porcine… Expand
Highly Cited
1989
Highly Cited
1989
Peptidyl-prolyl cis-trans isomerase (PPIase) catalyses the cis-trans isomerization of proline imidic peptide bonds in… Expand
Highly Cited
1989
Highly Cited
1989
CYCLOSPORIN A and the newly discovered immunosuppressant, FK-506, are potent inhibitors of T cell activation1. In addition to… Expand
Highly Cited
1984
Highly Cited
1984
Cyclophilin, a specific cytosolic binding protein responsible for the concentration of the immunosuppressant cyclosporin A by… Expand