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Cyclophilins

Known as: Cyclophilin, Cyclophilins [Chemical/Ingredient], Cyclosporin-Binding Proteins 
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
National Institutes of Health

Related topics

Related topics

18 relations
In BloodPPIase activityProcess of secretionantagonists & inhibitors

Narrower (9)

PPID protein, humanPPIG protein, humanPeptidylprolyl IsomeraseSQN protein, Arabidopsis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Cyclophilin inhibitors in hepatitis C viral infection
Cyclophilins (Cyps) are proteins that are ubiquitously present with peptidyl-prolyl cis-trans isomerase activity and play an… 
2002
2002
Parallel channels and rate-limiting steps in complex protein folding reactions: prolyl isomerization and the alpha subunit of Trp synthase, a TIM barrel protein.
2000
2000
Oxygen Stress Increases Prolyl cis/trans Isomerase Activity and Expression of Cyclophilin 18 in Rabbit Blastocysts
Abstract The peptidyl-prolyl cis/trans isomerase (PPIase) activity and the expression of cyclophilins were studied in 6-day-old… 
1999
1999
Stress-induced expression of cyclophilins in proembryonic masses of Digitalis lanata does not protect against freezing/thawing stress
Abstract. Using proembryonic masses (PEMs) of Digitalis lanata Erh., it was demonstrated that cold, hormonal or osmotic stress… 
1996
1996
A cyclophilin‐like peptidyl‐prolyl cis/trans isomerase from Legionella pneumophila – characterization, molecular cloning and overexpression
Legionella pneumophila is the causative agent of a severe form of pneumonia in humans (Legionnaires’disease). A major virulence… 
1993
1993
Kinetics of folding and association of differently glycosylated variants of invertase from saccharomyces cerevisiae
A core‐glycosylated form of the dimeric enzyme invertase has been isolated from secretion mutants of Saccharomyces cerevisiae… 
1993
1993
Altered levels and splicing of the amyloid precursor protein in the adult rat hippocampus after treatment with DMSO or retinoic acid.
1992
1992
Solution structure of cyclosporin A and a nonimmunosuppressive analog bound to fully deuterated cyclophilin.
A simple strategy involving 1H nuclear magnetic resonance (NMR) spectroscopy and complete protein deuteration was used to… 
1992
1992
Identification of actin and HSP 70 as cyclosporin A binding proteins by photoaffinity labeling and fluorescence displacement assays.
1992
1992
Streptomycetes possess peptidyl‐prolyl cis‐trans isomerases that strongly resemble cyclophilins from eukaryotic organisms
A functionally active 17.5 kDa peptidyl‐prolyl cis‐trans isomerase was purified to homogeneity from Streptomyces chrysomallus, a… 
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