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Immunophilins

Known as: Immunophilins [Chemical/Ingredient] 
Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (1)

FPR3 protein, S cerevisiae
In BloodNeurophilinsPPIase activityProcess of secretion

Broader (1)

Peptidylprolyl Isomerase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Immunophilins and HIV-1 V3 Loop For Structure-Based Anti-AIDS Drug Design
Abstract The model of the structural complex of cyclophilin A (CycA) belonging to the immunophilins family with the HIV-MN gpl20… 
2004
2004
Introducing Immunophilins. From Organ Transplantation to Plant Biology
The discovery of the family of highly effective and specific fungal metabolites cyclosporin, FK-506, and rapamycin ranks among… 
Review
2003
Review
2003
Immunophilins and coupled gating of ryanodine receptors.
The ryanodine receptor (RyR) is the major calcium (Ca(2+)) release channel in the sarcoplasmic reticulum (SR) of skeletal and… 
Review
2003
Review
2003
Therapeutic implications for immunophilin ligands in the treatment of neurodegenerative diseases.
  • K. PongM. Zaleska
  • Current Drug Targets - CNS & Neurological…
  • 2003
  • Corpus ID: 28922506
There is a significant unmet need for therapeutic agents in the treatment of neurodegenerative diseases. Given their clinical… 
2002
2002
Immunophilins and HIV-1 infection
Summary. Peptides of the V3 loop of the HIV-1 envelope glycoprotein gp120 have been shown to bind with high affinity to the… 
1999
1999
Cyclosporin A regulates the levels of cyclophilin A in neuroblastoma cells in culture
1998
1998
Purification of Hsp90 partner proteins Hop/p60, p23, and FKBP52.
1998
1998
Immunophilins in animals and higher plants
Immunophilins were originally discovered as receptors for a family of immunosuppressive drugs including cyclosporin, FK506, and… 
Review
1995
Review
1995
Receptor (Immunophilin‐Bhiding) Assay for Immunosuppressive Drugs
Summary The major immunophilins that bind cyclosporine (cyclophilin) and FK-506/rapamycin (FK-BP12) have been well characterized… 
Review
1994
Review
1994
Molecular and biological actions of cyclosporin A and FK506 on T cell development and function.
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