Immunophilins

Known as: Immunophilins [Chemical/Ingredient] 
Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0102019902018

Papers overview

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Highly Cited
2006
Highly Cited
2006
The immunophilin-like protein TWISTED DWARF1 (TWD1/FKBP42) has been shown to physically interact with the multidrug resistance/P… (More)
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Highly Cited
2005
Highly Cited
2005
We used a cellular system to elucidate the molecular determinants of the large immunophilin FK506-binding proteins (FKBP)51 and… (More)
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2004
2004
The tumor suppressor protein p53 is known to be transported to the nucleus along microtubular tracks by cytoplasmic dynein… (More)
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Highly Cited
2002
Highly Cited
2002
We have identified a new first step in the hormonal activation of the glucocorticoid receptor (GR). Rather than causing immediate… (More)
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Highly Cited
2000
Highly Cited
2000
MYC affects normal and neoplastic cell proliferation by altering gene expression, but the precise pathways remain unclear. We… (More)
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Highly Cited
1999
Highly Cited
1999
Squirrel monkeys are neotropical primates that have high circulating cortisol to compensate for expression of glucocorticoid… (More)
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Highly Cited
1994
Highly Cited
1994
THE immunosuppressive action of the drug FK506 involves inhibition of calcineurin in T-lymphocytes by a complex of FK506 and an… (More)
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Highly Cited
1992
Highly Cited
1992
THE immunophilins cyclophilin and FK506 binding protein (FKBP) are small, predominantly soluble proteins that bind the… (More)
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Highly Cited
1992
Highly Cited
1992
Calcineurin, a Ca2+, calmodulin-dependent protein phosphatase, was recently found to bind with high affinity to two different… (More)
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Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… (More)
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