POR protein, human

Known as: NADPH--Cytochrome P450 Reductase, EC 1.6.2.4, NADPH-Specific Cytochrome C Reductase 
NADPH-cytochrome P450 reductase (677 aa, ~77 kDa) is encoded by the human POR gene. This protein plays a role in electron transfer.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The purpose of the present study was to determine the absolute protein expression levels of multiple drug-metabolizing enzymes… (More)
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2011
2011
The microsomal, membrane-bound, human cytochrome P450 (CYP) 2C9 is a liver-specific monooxygenase essential for drug metabolism… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Complete chest wall recoil improves hemodynamics during cardiopulmonary resuscitation (CPR) by generating relatively… (More)
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2005
2005
Drug-metabolizing enzymes and drug transporters are key determinants of the pharmacokinetics and pharmacodynamics of many… (More)
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2004
2004
Cytochrome P450 (CYP) gene transfer sensitizes tumor xenografts to anticancer prodrugs such as cyclophosphamide (CPA) without a… (More)
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2004
2004
Renal cell carcinoma (RCC) is the most common malignancy of the kidney and has a poor prognosis due to its late presentation and… (More)
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2002
2002
The kinetics of internal electron transfer in human cytochrome P450 reductase have been studied using temperature-jump relaxation… (More)
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1999
1999
The crystal structure of the FMN-binding domain of human NADPH-cytochrome P450 reductase (P450R-FMN), a key component in the… (More)
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1999
1999
The widely accepted catalytic cycle of cytochromes P450 (CYP) involves the electron transfer from NADPH cytochrome P450 reductase… (More)
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1997
1997
Regulated cell cycle progression depends on the proper integration of growth control pathways with the basic cell cycle machinery… (More)
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