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POR protein, human

Known as: NADPH--Cytochrome P450 Reductase, EC 1.6.2.4, NADPH-Specific Cytochrome C Reductase 
NADPH-cytochrome P450 reductase (677 aa, ~77 kDa) is encoded by the human POR gene. This protein plays a role in electron transfer.
National Institutes of Health

Related topics

Related topics

10 relations
AromataseEnzyme GeneEstrogen Metabolic ProcessNADPH-ferrihemoprotein reductase activity

Broader (2)

Cytochrome P450NADPH-Ferrihemoprotein Reductase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer.
Cytochrome P450 reductase (CPR) is a tethered membrane protein which transfers electrons from NADPH to microsomal P450s. We show… 
2007
2007
Adrenodoxin supports reactions catalyzed by microsomal steroidogenic cytochrome P450s.
Highly Cited
2003
Highly Cited
2003
Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues.
The role of coenzyme binding in regulating interflavin electron transfer in human cytochrome P450 reductase (CPR) has been… 
2003
2003
Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1.
Human novel reductase 1 (NR1) is an NADPH dependent diflavin oxidoreductase related to cytochrome P450 reductase (CPR). The FAD… 
Highly Cited
2001
Highly Cited
2001
Stopped-flow kinetic studies of flavin reduction in human cytochrome P450 reductase and its component domains.
The reduction by NADPH of the FAD and FMN redox centers in human cytochrome P450 reductase and its component domains has been… 
2001
2001
Distribution of DT-diaphorase and reduced nicotinamide adenine dinucleotide phosphate: cytochrome p450 oxidoreductase in bladder tissues and tumors.
2000
2000
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
The kinetics of flavin reduction in two mutant forms of human cytochrome P450 reductase have been studied by stopped-flow… 
2000
2000
Identification of key residues in rabbit liver microsomal cytochrome P450 2B4: importance in interactions with NADPH-cytochrome P450 reductase.
A cytochrome P450 2B4 (CYP2B4) model was used to select key residues supposed to serve in interactions with NADPH-cytochrome P450… 
1999
1999
Carbonyl reductase and NADPH cytochrome P450 reductase activities in human tumoral versus normal tissues.
Highly Cited
1997
Highly Cited
1997
Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
Regulated cell cycle progression depends on the proper integration of growth control pathways with the basic cell cycle machinery… 
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