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POR protein, human

Known as: NADPH--Cytochrome P450 Reductase, EC 1.6.2.4, NADPH-Specific Cytochrome C Reductase 
NADPH-cytochrome P450 reductase (677 aa, ~77 kDa) is encoded by the human POR gene. This protein plays a role in electron transfer.
National Institutes of Health

Related topics

Related topics

10 relations
AromataseEnzyme GeneEstrogen Metabolic ProcessNADPH-ferrihemoprotein reductase activity

Broader (2)

Cytochrome P450NADPH-Ferrihemoprotein Reductase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well…
Cytochrome P450 NADPH-reductase (P450R), inducible synthase (iNOS) and xanthine oxidase play an important role in the… 
2010
2010
Sequence–function correlation of aromatase and its interaction with reductase
2008
2008
Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.
2003
2003
Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1.
Human novel reductase 1 (NR1) is an NADPH dependent diflavin oxidoreductase related to cytochrome P450 reductase (CPR). The FAD… 
Highly Cited
2001
Highly Cited
2001
Stopped-flow kinetic studies of flavin reduction in human cytochrome P450 reductase and its component domains.
The reduction by NADPH of the FAD and FMN redox centers in human cytochrome P450 reductase and its component domains has been… 
2001
2001
Distribution of DT-diaphorase and reduced nicotinamide adenine dinucleotide phosphate: cytochrome p450 oxidoreductase in bladder tissues and tumors.
2000
2000
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
The kinetics of flavin reduction in two mutant forms of human cytochrome P450 reductase have been studied by stopped-flow… 
2000
2000
Identification of key residues in rabbit liver microsomal cytochrome P450 2B4: importance in interactions with NADPH-cytochrome P450 reductase.
A cytochrome P450 2B4 (CYP2B4) model was used to select key residues supposed to serve in interactions with NADPH-cytochrome P450… 
1999
1999
Some properties of mitochondrial adrenodoxin associated with its nonconventional electron donor function toward rabbit liver microsomal cytochrome P450 2B4.
Mitochondrial adrenodoxin (Adx) was found to cross-react with microsomal cytochrome P450 2B4 (CYP2B4) as the terminal electron… 
1994
1994
Kinetic mechanism for the model reaction of NADPH-cytochrome P450 oxidoreductase with cytochrome c.
The kinetic mechanism of NADPH-cytochrome P450 oxidoreductase (P450R) has been determined for the model reaction with cytochrome… 
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