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NADPH-Ferrihemoprotein Reductase
Known as:
Oxidase, Cytochrome P-450
, P-450 Oxidase, Cytochrome
, P450 Reductase, NADPH-Cytochrome
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A flavoprotein that catalyzes the reduction of heme-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. EC 1.6.2.4.
National Institutes of Health
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Related topics
Related topics
14 relations
Antley-Bixler Syndrome Phenotype
Cytochrome c Reductase
In Blood
NADPH-ferrihemoprotein reductase activity
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Narrower (3)
CPRR2 protein, cotton
POR protein, human
flavocytochrome P450 BM3 monoxygenases
Broader (1)
Oxidoreductase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.
D. Davydov
,
Harshica Fernando
,
B. Baas
,
S. Sligar
,
J. Halpert
Biochemistry
2005
Corpus ID: 44962113
To explore the basis of apparent conformational heterogeneity of cytochrome P450 3A4 (CYP3A4), the kinetics of dithionite…
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1994
1994
Membrane potential-linked reversed electron transfer in the beef heart cytochrome bc1 complex reconstituted into potassium-loaded phospholipid vesicles.
Toshiaki Miki
,
M. Miki
,
Yutaka Orii
Journal of Biological Chemistry
1994
Corpus ID: 45992398
Highly Cited
1984
Highly Cited
1984
On the mechanism of action of cytochrome P-450. Oxidation and reduction of the ferrous dioxygen complex of liver microsomal cytochrome P-450 by cytochrome b5.
D. Pompon
,
M. J. Coon
Journal of Biological Chemistry
1984
Corpus ID: 747561
Highly Cited
1983
Highly Cited
1983
Oxidation-reduction properties of rat liver cytochromes P-450 and NADPH-cytochrome p-450 reductase related to catalysis in reconstituted systems.
F. Guengerich
Biochemistry
1983
Corpus ID: 26023348
A series of equilibrium and kinetic measurements involving the oxidation-reduction properties of purified rat liver NADPH…
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Highly Cited
1978
Highly Cited
1978
The electronic state of heme in cytochrome oxidase II. Oxidation-reduction potential interactions and heme iron spin state behavior observed in reductive titrations.
G. Babcock
,
L. Vickery
,
G. Palmer
Journal of Biological Chemistry
1978
Corpus ID: 22793400
Highly Cited
1977
Highly Cited
1977
Studies on the microsomal electron-transport system of anaerobically grown yeast. V. Purification and characterization of NADPH-cytochrome c reductase.
S. Kubota
,
Y. Yoshida
,
H. Kumaoka
,
A. Furumichi
Journal of Biochemistry (Tokyo)
1977
Corpus ID: 30129275
A flavoprotein catalyzing the reduction of cytochrome c by NADPH was solubilized and purified from microsomes of yeast grown…
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Highly Cited
1975
Highly Cited
1975
Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential.
F. Guengerich
,
D. Ballou
,
M. Coon
Journal of Biological Chemistry
1975
Corpus ID: 38772061
Highly Cited
1971
Highly Cited
1971
Microsomal electron transport reactions. I. Interaction of reduced triphosphopyridine nucleotide during the oxidative demethylation of aminopyrine and cytochrome b 5 reduction.
Beverly S. Cohen
,
Ronald W. Estabrook
Archives of Biochemistry and Biophysics
1971
Corpus ID: 7414118
Highly Cited
1971
Highly Cited
1971
Effect of various inducers on electron transport system associated with drug metabolism by liver microsomes.
J. Gillette
Metabolism: Clinical and Experimental
1971
Corpus ID: 37102188
Highly Cited
1966
Highly Cited
1966
Evidence for two forms of P-450 hemoprotein in microsomal membranes.
Y. Imai
,
R. Sato
Biochemical and Biophysical Research…
1966
Corpus ID: 30473871
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