NADPH-ferrihemoprotein reductase activity

Known as: NADPH:P450 reductase activity, NADPH--cytochrome P450 reductase activity, NADPH--cytochrome P450 oxidoreductase activity 
Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein. [EC:1.6.2.4]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2017
010203019662017

Papers overview

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Review
2015
Review
2015
Liver fibrosis is the pathological consequence of chronic liver diseases, where an excessive deposition of extracellular matrix… (More)
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Highly Cited
2013
Highly Cited
2013
Stimulus-specific accumulation of second messengers like reactive oxygen species (ROS) and Ca(2+) are central to many signaling… (More)
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Highly Cited
2010
Highly Cited
2010
RATIONALE NADPH oxidases are a major source of superoxide (O(2)(-)) in the cardiovascular system. The function of Nox4, a member… (More)
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Highly Cited
2009
Highly Cited
2009
Abundant evidence leaves no doubt that reactive oxygen species (ROS) are not only inevitable by-products of oxygen metabolism but… (More)
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Highly Cited
2008
Highly Cited
2008
A large body of literature suggest that vascular reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases are… (More)
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Highly Cited
2005
Highly Cited
2005
CD95 ligand (CD95L) triggers a rapid formation of reactive oxygen species (ROS) as an upstream event of CD95 activation and… (More)
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Highly Cited
2003
Highly Cited
2003
Interactions of polymorphonuclear neutrophils (PMNs) with endothelial cells may contribute to the activation of endothelial cell… (More)
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Highly Cited
1992
Highly Cited
1992
Nitric oxide synthases (NOS Types I-III) generate nitric oxide (NO), which in turn activates soluble guanylyl cyclase (GC-S). The… (More)
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Highly Cited
1992
Highly Cited
1992
Neuronal nitric oxide synthase (NOS), an enzyme capable of synthesizing nitric oxide, appears to be identical to neuronal NADPH… (More)
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Highly Cited
1989
Highly Cited
1989
We examined the properties of neuronal NADPH-diaphorase in sections of rat striatum, using histochemical procedures. NADPH… (More)
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