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PLA2G4B protein, human

Known as: HsT16992, cytosolic phospholipase A2 beta, human, PLA2G4B 
Cytosolic phospholipase A2 beta (781 aa, ~88 kDa) is encoded by the human PLA2G4B gene. This protein plays a role in glycerophospholipid metabolism.
National Institutes of Health

Related topics

Related topics

21 relations
Arachidonic Acid Metabolism PathwayC2 DomainsCalcium BindingEnzyme Gene
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Broader (1)

Cytosolic Phospholipase A2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Cytosolic Phospholipase A2 Protein as a Novel Therapeutic Target for Spinal Cord Injury
Objective The objective of this study was to investigate whether cytosolic phospholipase A2 (cPLA2), an important isoform of PLA2… Expand
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2009
2009
Cytosolic phospholipase A2-driven PGE2 synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells.
Cytoplasmic lipid bodies (also known as lipid droplets) are intracellular deposits of arachidonic acid (AA), which can be… Expand
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2007
2007
Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase
Singlet oxygen is a highly reactive form of molecular oxygen that may harm living systems by oxidizing critical cellular… Expand
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Review
2006
Review
2006
Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s.
Phospholipase A(2) (PLA(2)) (EC 3.1.1.4) catalyzes hydrolysis of the sn-2 ester bond of glycerophospholipids. The enzyme is… Expand
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Highly Cited
2004
Highly Cited
2004
Cryptochromes and neuronal-activity markers colocalize in the retina of migratory birds during magnetic orientation.
Migratory birds can use a magnetic compass for orientation during their migratory journeys covering thousands of kilometers. But… Expand
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Highly Cited
2003
Highly Cited
2003
Deletion of cytosolic phospholipase A2 promotes striated muscle growth
Generation of arachidonic acid by the ubiquitously expressed cytosolic phospholipase A2 (PLA2) has a fundamental role in the… Expand
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Highly Cited
1999
Highly Cited
1999
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain.
The mechanism by which chronic lithium exerts its therapeutic effect in brains of bipolar patients is not known. One possibility… Expand
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Highly Cited
1999
Highly Cited
1999
Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration.
Many recent studies have emphasized the deleterious role of inflammation in CNS injury. Increases in free fatty acids… Expand
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Highly Cited
1996
Highly Cited
1996
Reactive glia express cytosolic phospholipase A2 after transient global forebrain ischemia in the rat.
BACKGROUND AND PURPOSE Phospholipid breakdown has been reported to be an early event in the brain after global cerebral ischemia… Expand
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1996
1996
Cytosolic Phospholipase A2 (PLA2), but Not Secretory PLA2, Potentiates Hydrogen Peroxide Cytotoxicity in Kidney Epithelial Cells*
Phospholipase A2 (PLA2) and reactive oxygen species have been implicated both individually and synergistically in various forms… Expand
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