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PK 11195

Known as: PK-11195, PK11195 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antineoplastic AgentsIsoquinolines
RP 52028

Papers overview

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2014
2014
Translocator protein (18 kDa) mapping with [125I]-CLINDE in the quinolinic acid rat model of excitotoxicity: a longitudinal comparison with microglial activation, astrogliosis, and neuronal death.
Excitotoxicity leads to an inflammatory reaction involving an overexpression of: translocator protein 18 kDa (TSPO) in cerebral… 
2014
2014
[Neurosteroidogenesis and exploratory responses in rodents].
We have studied the influence of intraperitoneal introduction of a selective blocker of mitochondrial translocation protein 18kD… 
2013
2013
[C-11]PK13168 and [C-11]PK13162, two PK11195 analogues labelled at their carbamate function using [C-11]phosgene
2009
2009
A Single Amino Acid Controls the Functional Switch of Human Constitutive Androstane Receptor ( CAR ) 1 to the Xenobiotic-Sensitive Splicing Variant CAR 3
The constitutive androstane receptor (CAR) is constitutively activated in immortalized cell lines independent of xenobiotic… 
Review
2009
Review
2009
SOCIETA’ ITALIANA DI
PMID: 18368909 [PubMed indexed for MEDLINE] 4: Brain Res Bull. 2008 Mar 28;75(5):668-73. Epub 2007 Dec 3. The effect of… 
2002
2002
In-vivo-Darstellung „neuroinflammatorischer” Veränderungen mit [11C] PK11195-PET
R R R (R 
2000
2000
In vivo reversal of apoptosis resistance by the mitochondrial benzodiazepine receptor antagonist, PK11195 in cholangiocarcinoma cells
1990
1990
Effect of PK11195 on cardiovascular toxicity due to verapamil: an experimental study in the dog.
In vitro studies have suggested that peripheral binding sites (PBR) for benzodiazepine (BZD) could be coupled to the voltage… 
1989
1989
[Variation in the urinary excretion of 6-beta-hydroxycortisol in humans after administration of the new isoquinoline derivative, PK-11195 (52028 RP)].
Among in vivo tests to assess liver drug metabolizing enzyme induction, urinary 6-beta-hydroxycortisol (6-beta-OHF), plasma gamma… 
1988
1988
In vivo immunomodulating activity of PK11195, a structurally unrelated ligand for peripheral benzodiazepine binding sites. The possible involvement of central cervous system receptors