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PK 11195

Known as: PK-11195, PK11195 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antineoplastic AgentsIsoquinolines
RP 52028

Papers overview

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Highly Cited
2015
Highly Cited
2015
In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET.
Highly Cited
2005
Highly Cited
2005
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum
Highly Cited
2003
Highly Cited
2003
Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
Mda-7/IL-24 (Ad.mda-7) is a novel cytokine gene belonging to the interleukin (IL) 10 gene superfamily. Adenoviral-mediated… 
Review
2003
Review
2003
Mitochondria as a Target for Inducing Death of Malignant Hematopoietic Cells
Mitochondria plays a central role in apoptotic cell death. The intermembrane space of mitochondria contains a number of soluble… 
Highly Cited
2001
Highly Cited
2001
REDUCTION OF ACUTE INFLAMMATION IN RATS BY DIAZEPAM: ROLE OF PERIPHERAL BENZODIAZEPINE RECEPTORS AND CORTICOSTERONE
Carrageenin causes a reproducible inflammatory reaction and remains the standard irritant for examining acute inflammation and… 
Highly Cited
1998
Highly Cited
1998
The role of GABA-A and mitochondrial diazepam-binding inhibitor receptors on the effects of neurosteroids on food intake in mice
Abstract The present studies were undertaken to investigate the neuroactive steroidal modulation of feeding behavior and possible… 
Highly Cited
1998
Highly Cited
1998
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells.
Highly Cited
1997
Highly Cited
1997
The M r 18,000 Subunit of the Peripheral-type Benzodiazepine Receptor Exhibits Both Benzodiazepine and Isoquinoline Carboxamide Binding Sites in the Absence of the Voltage-dependent Anion Channel or…
The peripheral type benzodiazepine receptor (PBR) binds benzodiazepines such as RO5-4864 and isoquinoline carboxamide derivatives… 
1996
1996
The effect of propofol on CA1 pyramidal cell excitability and GABAA-mediated inhibition in the rat hippocampal slice.
1984
1984
Pro‐ and anti‐convulsant properties of PK 11195, a ligand for benzodiazepine binding sites: development of tolerance
1 Ro 5–4864 is a benzodiazepine that differs from diazepam only in a p‐chloro substituent and yet is inactive at the classical… 
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