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A highly significant association between a COMT haplotype and schizophrenia.
TLDR
An efficient approach to gene discovery is reported that found a highly significant association between schizophrenia and a COMT haplotype and can be widely implemented for the genetic dissection of other common diseases.
Enigma of the peripheral benzodiazepine receptor.
Benzodiazepines (BZs)2 are used clinically as muscle relaxants, anticonvulsants, anxiolytics, and sedative-hypnotics. These effects are mediated primarily via the central BZ receptors (CBRs) located
Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine.
TLDR
Olanzapine-induced weight gain is associated with a general increase in caloric intake and not in those given haloperidol.
Reliability and validity of the Family Eating and Activity Habits Questionnaire
TLDR
The Family Activity and Eating Habits Questionnaire is reliable and internally consistent, and it is useful as an optional tool for planning an intervention program for childhood obesity.
Obsessive-compulsive disorder in patients with first-episode schizophrenia.
TLDR
OCD is relatively frequent in patients with first-episode schizophrenia and may have a "protective" effect on some schizophrenic symptoms, at least in the early stages of the disease.
Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.
TLDR
Findings validate previous findings that this condition is one of the strongest risk factors for psychosis and highlight the need to monitor and reduce the long-term burden of psychopathology in 22q11.2 deletion syndrome.
Psychiatric disorders and intellectual functioning throughout development in velocardiofacial (22q11.2 deletion) syndrome.
TLDR
The VIQ scores are negatively associated with age and rates of mood, and psychotic disorders increase dramatically during young adulthood, and neuropsychiatric deficits in individuals with VCFS seem to follow a developmental pattern.
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