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PCSK1 protein, human

Known as: proprotein convertase subtilisin-kexin type 1, human, Proprotein Convertase Subtilisin/Kexin-Type 1, Neuroendocrine Convertase 1 
Neuroendocrine convertase 1 (753 aa, ~84 kDa) is encoded by the human PCSK1 gene. This protein plays a role in the proteolytic activation of protein… 
National Institutes of Health

Related topics

Related topics

12 relations
EndopeptidasesEnzyme GeneHydrolysisIntegral Membrane Proteins

Broader (1)

Proprotein Convertase 1

Papers overview

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2016
2016
Characterization of endoproteolytic processing of dynorphins by proprotein convertases using mouse spinal cord S9 fractions and mass spectrometry
2014
2014
Structural Studies on Human Calpain-3 Protease Core
Skeletal muscle-specific protein calpain-3 (CAPN3/p94) is a member of the calcium-dependent cysteine protease family. CAPN3 is… 
2010
2010
An interpretation of positional displacement of the helix12 in nuclear receptors: preexistent swing-up motion triggered by ligand binding.
2003
2003
Expression, purification, and PC1-mediated processing of (H10D, P28K, and K29P)-human proinsulin.
2003
2003
Expression, purification, and PC1-mediated processing of human proglucagon, glicentin, and major proglucagon fragment.
2002
2002
Functional Characterization of ProSAAS
Prohormone convertases (PC) 1 and 2, enzymes found primarily in neuroendocrine tissues, are thought to mediate the proteolytic… 
1998
1998
PC 5-A-mediated Processing of Pro-neurotensin in Early Compartments of the Regulated Secretory Pathway of PC 5-transfected PC 12 Cells
Among the members of the proprotein convertase (PC) family, PC1 and PC2 have well established roles as prohormone convertases… 
1995
1995
Mutational Analysis of PC1 (SPC3) in PC12 Cells
The proteinase mPC1, a neuroendocrine member of the mammalian family of subtilisin-like enzymes, has previously been shown to be… 
1995
1995
Structural investigation and kinetic characterization of potential cleavage sites of HIV GP160 by human furin and PC1.
A key event in the biosynthesis of the human immunodeficiency virus is the maturation of the gp160 precursor generating gp120 and… 
1995
1995
Expression of antisense PC1 in stably transfected RIN5F cells significantly reduces CCK 8 biosynthesis
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