PCSK1 protein, human

Known as: proprotein convertase subtilisin-kexin type 1, human, Proprotein Convertase Subtilisin/Kexin-Type 1, Neuroendocrine Convertase 1 
Neuroendocrine convertase 1 (753 aa, ~84 kDa) is encoded by the human PCSK1 gene. This protein plays a role in the proteolytic activation of protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Proglucagon is cleaved to glucagon by prohormone convertase 2 (PC2) in pancreatic α-cells, but is cleaved to glucagon-like… (More)
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2000
2000
Prohormone convertases (PCs) 1 and 2 are thought to mediate the proteolytic cleavage of many peptide precursors. Endogenous… (More)
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2000
2000
ProSAAS is a recently discovered 26-kDa neuroendocrine protein that was previously found to inhibit prohormone convertase (PC) 1… (More)
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1998
1998
Proglucagon (proG) is differentially processed in the A cells of the pancreas to yield glucagon, and in the L cells of the… (More)
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1996
1996
To investigate the factors involved in the post-translational processing of proglucagon, we have examined the proglucagon-derived… (More)
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1995
1995
Secretoneurin is a recently characterized neuropeptide present in the primary amino acid sequence of secretogranin II. We… (More)
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Highly Cited
1994
Highly Cited
1994
The genes encoding mammalian subtilisin-like endoproteases furin, PC1, and PC2 have been isolated and are implicated in… (More)
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1994
1994
The immunocytochemical distribution and messenger RNA expression of the prohormone convertases PC1 and PC2 involved in the… (More)
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1993
1993
The prohormone convertases PC1 (also known as PC3) and PC2 have been implicated in the biosynthesis of several polypeptide… (More)
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1992