• Publications
  • Influence
Mice Lacking Specific Nicotinic Acetylcholine Receptor Subunits Exhibit Dramatically Altered Spontaneous Activity Patterns and Reveal a Limited Role for Retinal Waves in Forming ON and OFF Circuits
Before phototransduction, spontaneous activity in the developing mammalian retina is required for the appropriate patterning of retinothalamic connections, and there is growing evidence that thisExpand
  • 328
  • 42
  • PDF
Prolonged Morphine Treatment Targets δ Opioid Receptors to Neuronal Plasma Membranes and Enhances δ-Mediated Antinociception
Opioid receptors are known to undergo complex regulatory changes in response to ligand exposure. In the present study, we examined the effect of morphine on the in vitro and in vivo density andExpand
  • 215
  • 26
  • PDF
Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons
The serotoninergic (5-hydroxytryptamine, 5-HT) innervation of the rat ventral tegmental area (VTA) was examined by light and electron microscopic radioautography following intraventricular infusionExpand
  • 379
  • 15
Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception.
Opioid receptors are known to undergo complex regulatory changes in response to ligand exposure. In the present study, we examined the effect of morphine on the in vitro and in vivo density andExpand
  • 119
  • 15
Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of Acra7-deficient mice.
The alpha7 nicotinic acetylcholine receptor (nAChR) subunit is abundantly expressed in the hippocampus and contributes to hippocampal cholinergic synaptic transmission suggesting that it mayExpand
  • 301
  • 14
The serotonin neurons in nucleus raphe dorsalis of adult rat: A light and electron microscope radioautographic study
The serotoninergic nerve cell body population of nucleus raphe dorsalis (RD) was identified by radioautography following cerebroventricular instillation of tritiated serotonin ([3H]5‐HT) in adultExpand
  • 369
  • 13
Immunohistochemical distribution of delta opioid receptors in the rat central nervous system: Evidence for somatodendritic labeling and antigen‐specific cellular compartmentalization
Many studies have reported on the distribution of delta opioid receptors (δOR) in the mammalian central nervous system (CNS) by using a variety of techniques. However, no general consensus hasExpand
  • 125
  • 13
Morphine and Pain-Related Stimuli Enhance Cell Surface Availability of Somatic δ-Opioid Receptors in Rat Dorsal Root Ganglia
The present study demonstrates that perikaryalδ-opioid receptors (δORs) in rat dorsal root ganglion (DRG) neurons bind and internalize opioid ligands circulating in the CSF. Using confocal andExpand
  • 151
  • 12
Cellular distribution of neurotensin receptors in rat brain: Immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor
Receptors for the neuropeptide, neurotensin, were localized by immunohistochemistry in the rat brain by using an antibody raised against a sequence of the third intracellular loop of the cloned highExpand
  • 170
  • 11
Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system
In the present study, we localized the levocabastine‐sensitive neurotensin receptor (NTS2) protein in adult rat brain by using an N‐terminally‐directed antibody. NTS2‐like immunoreactivity wasExpand
  • 102
  • 11