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Oxotremorine

Known as: 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, Oxotremorine [Chemical/Ingredient], Oxytremorine 
A non-hydrolyzed muscarinic agonist used as a research tool.
National Institutes of Health

Related topics

Related topics

16 relations

Broader (5)

Cholinergic AgentsGanglionic StimulantsMuscarinic AgonistsPyrrolidinones
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

N-methylacetamide-oxotremorine MU 80816Boxotremorine Moxotremorine sesquifumarate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Cyclic and Sleep-Like Spontaneous Alternations of Brain State Under Urethane Anaesthesia
Background Although the induction of behavioural unconsciousness during sleep and general anaesthesia has been shown to involve… 
Highly Cited
1999
Highly Cited
1999
Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation
Ample research indicates that age-related neuronal–behavioral decrements are the result of oxidative stress that may be… 
Highly Cited
1992
Highly Cited
1992
Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum, and hippocampus of the rat.
Highly Cited
1991
Highly Cited
1991
The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.
Highly Cited
1985
Highly Cited
1985
Antinociceptive effects of intrathecally injected cholinomimetic drugs in the rat and cat.
Highly Cited
1976
Highly Cited
1976
SODIUM‐DEPENDENT HIGH AFFINITY CHOLINE UPTAKE: A REGULATORY STEP IN THE SYNTHESIS OF ACETYLCHOLINE
The sodium‐dependent high affinity choline uptake into synaptosomes from rat brain has been studied after in vivo treatments… 
Highly Cited
1975
Highly Cited
1975
Utilization of sodium-dependent high affinity choline uptake in vitro as a measure of the activity of cholinergic neurons in vivo.
Highly Cited
1972
Highly Cited
1972
Three acetylcholine receptors in Aplysia neurones
  • J. Kehoe
  • Journal of Physiology
  • 1972
  • Corpus ID: 12874104
1. In the pleural ganglion of Aplysia californica, groups of cells were identified that respond differently to an iontophoretic… 
Highly Cited
1972
Highly Cited
1972
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Effects of acetylcholine and of agents that mimic or block its physiological actions have been studied upon concentrations of… 
Highly Cited
1964
Highly Cited
1964
A CHOLINERGIC MECHANISM IN THE BRAINSTEM RETICULAR FORMATION: INDUCTION OF PARADOXICAL SLEEP.
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