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Oxotremorine

Known as: 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, Oxotremorine [Chemical/Ingredient], Oxytremorine 
A non-hydrolyzed muscarinic agonist used as a research tool.
National Institutes of Health

Related topics

Related topics

16 relations

Broader (5)

Cholinergic AgentsGanglionic StimulantsMuscarinic AgonistsPyrrolidinones
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

N-methylacetamide-oxotremorine MU 80816Boxotremorine Moxotremorine sesquifumarate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1992
Highly Cited
1992
Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism
Highly Cited
1992
Highly Cited
1992
Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons
Highly Cited
1984
Highly Cited
1984
Cholinergic drug effects and brain muscarinic receptor binding in aged rats
Highly Cited
1982
Highly Cited
1982
Differential alterations of cholinergic muscarinic receptors during chronic and acute tolerance to organophosphorus insecticides.
Highly Cited
1981
Highly Cited
1981
Autoregulation of acetylcholine release in isolated hippocampal nerve endings.
Highly Cited
1976
Highly Cited
1976
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
Highly Cited
1975
Highly Cited
1975
Utilization of sodium-dependent high affinity choline uptake in vitro as a measure of the activity of cholinergic neurons in vivo.
Highly Cited
1974
Highly Cited
1974
Centrally mediated bradycardia and hypotension induced by narcotic analgesics: dextromoramide and fentanyl.
Highly Cited
1972
Highly Cited
1972
Acetylcholine receptors: topographic distribution and pharmacological properties of two receptor types on a single molluscan neurone
1. The iontophoretic application of acetylcholine (ACh) on to identified neurones in the buccal ganglion of the mollusc Navanax… 
Highly Cited
1969
Highly Cited
1969
A TECHNIQUE FOR THE STUDY OF ACETYLCHOLINE TURNOVER IN MOUSE BRAIN IN VIVO
Abstract— —A method to measure the rate of acetylcholine turnover in mouse brain in vivo has been developed. It is based on the… 
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