Oxotremorine

Known as: 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, Oxotremorine [Chemical/Ingredient], Oxytremorine 
A non-hydrolyzed muscarinic agonist used as a research tool.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Although the induction of behavioural unconsciousness during sleep and general anaesthesia has been shown to involve… (More)
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Highly Cited
2002
Highly Cited
2002
Forebrain muscarinic acetylcholine (ACh) receptors (mAChRs; M1-M5) are predicted to play important roles in many fundamental… (More)
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Highly Cited
1999
Highly Cited
1999
Ample research indicates that age-related neuronal-behavioral decrements are the result of oxidative stress that may be… (More)
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Highly Cited
1999
Highly Cited
1999
G protein-coupled receptor kinase 5 (GRK5) is a member of a family of enzymes that phosphorylate activated G protein-coupled… (More)
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Highly Cited
1998
Highly Cited
1998
Recent research has indicated that increased vulnerability to oxidative stress may be the major factor involved in CNS functional… (More)
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1995
1995
cDNAs encoding for M1 and M3 muscarinic acetylcholine (ACh) receptors were detected in rat pancreatic islet cells by polymerase… (More)
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1985
1985
Saline, 8.0 mg/kg/hr nicotine, or 1.0 mg/kg/hr oxotremorine was continuously infused into the jugular veins of DBA female mice… (More)
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Highly Cited
1984
Highly Cited
1984
The mechanism underlying the regulation of the K-channel by the muscarinic receptor was examined with patch-clamp experiments in… (More)
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1979
1979
The immediate posttrial injection of oxotremorine (0.125, 0.250 and 0.500 μMol/kg i.p.) and equimolecular doses of physostigmine… (More)
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1972
1972
Effects of acetylcholine and of agents that mimic or block its physiological actions have been studied upon concentrations of… (More)
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