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Oxotremorine

Known as: 2-Pyrrolidinone, 1-(4-(1-pyrrolidinyl)-2-butynyl)-, Oxotremorine [Chemical/Ingredient], Oxytremorine 
A non-hydrolyzed muscarinic agonist used as a research tool.
National Institutes of Health

Related topics

Related topics

16 relations

Broader (5)

Cholinergic AgentsGanglionic StimulantsMuscarinic AgonistsPyrrolidinones
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (4)

N-methylacetamide-oxotremorine MU 80816Boxotremorine Moxotremorine sesquifumarate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Cyclic and Sleep-Like Spontaneous Alternations of Brain State Under Urethane Anaesthesia
Background Although the induction of behavioural unconsciousness during sleep and general anaesthesia has been shown to involve… Expand
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Highly Cited
1999
Highly Cited
1999
Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation
Ample research indicates that age-related neuronal–behavioral decrements are the result of oxidative stress that may be… Expand
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Highly Cited
1991
Highly Cited
1991
The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. A role for Gp in receptor compartmentation.
The relationship between muscarinic receptor activation of phosphoinositide hydrolysis and the sequestration of cell surface… Expand
Highly Cited
1984
Highly Cited
1984
Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation
Abstract: Characterisation of receptor‐mediated breakdown of inositol phospholipids in rat cortical slices has been performed… Expand
Highly Cited
1976
Highly Cited
1976
SODIUM‐DEPENDENT HIGH AFFINITY CHOLINE UPTAKE: A REGULATORY STEP IN THE SYNTHESIS OF ACETYLCHOLINE
The sodium‐dependent high affinity choline uptake into synaptosomes from rat brain has been studied after in vivo treatments… Expand
Highly Cited
1973
Highly Cited
1973
Depression of acetylcholine release from cerebral cortical slices by cholinesterase inhibition and by oxotremorine.
ACETYLCHOLINE (ACh) release from cholinergic terminals in the cerebral cortex can be measured after inhibiting Cholinesterase… Expand
Highly Cited
1972
Highly Cited
1972
Three acetylcholine receptors in Aplysia neurones
  • J. Kehoe
  • The Journal of physiology
  • 1972
    • Corpus ID: 12874104
1. In the pleural ganglion of Aplysia californica, groups of cells were identified that respond differently to an iontophoretic… Expand
Highly Cited
1972
Highly Cited
1972
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle.
Effects of acetylcholine and of agents that mimic or block its physiological actions have been studied upon concentrations of… Expand
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Highly Cited
1970
Highly Cited
1970
The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum.
Abstract Guanosine 3′, 5′ cyclic monophosphate (cGMP) and adenosine 3′,5′ cyclic monophosphate (cAMP) were measured in the… Expand
Highly Cited
1969
Highly Cited
1969
A TECHNIQUE FOR THE STUDY OF ACETYLCHOLINE TURNOVER IN MOUSE BRAIN IN VIVO
Abstract— —A method to measure the rate of acetylcholine turnover in mouse brain in vivo has been developed. It is based on the… Expand
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