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Oncogenes

Known as: Oncogene, Cancer-Promoting Gene, Genes, Transforming 
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of… 
National Institutes of Health

Related topics

Related topics

48 relations
BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315ICCDC6/RET Fusion ProteinCancer Promoting GenesCarcinogens

Narrower (11)

FOS Family GenesMYC Family GenesREL geneSRC gene

Broader (2)

GenesMutation

Papers overview

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2000
2000
Angiogenesis and the multistage development of lung cancers.
As with other epithelial tumors, lung cancers develop after a series of morphological and molecular changes. The molecular… 
Review
1991
Review
1991
Genes, oncogenes, and hormones : advances in cellular and molecular biology of breast cancer
I. The Progression of Node-Negative to -Positive Breast Cancer.- 1. Prognostic Factors in Axillary Node-Negative Breast Cancer… 
Review
1990
Review
1990
Oncogene amplification in neoplastic development and progression of human cancers.
Increased dosage of cellular oncogenes resulting from amplification of DNA is a frequent genetic abnormality of tumor cells… 
1989
1989
Activated oncogenes in human skin tumors from a repair-deficient syndrome, xeroderma pigmentosum.
The recessive autosomal hereditary disease, xeroderma pigmentosum (XP), is characterized by a high incidence of tumors in sun… 
1987
1987
Mapping of the oncogenes Myc, Sis, and int-1 to the distal part of mouse chromosome 15.
Two proto-oncogenes, Myc and Sis, as well as a putative mouse oncogene, int-1, were localized by in situ hybridization to the… 
1987
1987
Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.
Temperature-sensitive protein-tyrosine kinase (EC 2.7.1.112) mutants of the oncogene v-abl have been obtained by a direct… 
1986
1986
Growth factors, oncogenes and inositol lipids.
: Normal cells require growth factors to multiply. One group of growth factors such as platelet-derived growth factor, bombesin… 
1986
1986
Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells.
To determine the types of alterations in gene structure that are induced by the carcinogen 2-(N-acetoxy-N-acetyl)aminofluorene… 
Review
1985
Review
1985
NIH conference. Molecular genetic analysis of human lymphoid neoplasms. Immunoglobulin genes and the c-myc oncogene.
Immunoglobulin genes responsible for individual antibodies are organized as discontinuous DNA segments in their germline form. As… 
Review
1981
Review
1981
Retroviral gene expression.
Retroviruses1 have been extensively studied during the past 10–20 years. These viruses are of particular interest to molecular…