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Oncogenes

Known as: Oncogene, Cancer-Promoting Gene, Genes, Transforming 
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of… 
National Institutes of Health

Related topics

Related topics

48 relations
BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315ICCDC6/RET Fusion ProteinCancer Promoting GenesCarcinogens

Narrower (11)

FOS Family GenesMYC Family GenesREL geneSRC gene

Broader (2)

GenesMutation

Papers overview

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2000
2000
Angiogenesis and the multistage development of lung cancers.
As with other epithelial tumors, lung cancers develop after a series of morphological and molecular changes. The molecular… 
Review
1991
Review
1991
Genes, oncogenes, and hormones : advances in cellular and molecular biology of breast cancer
I. The Progression of Node-Negative to -Positive Breast Cancer.- 1. Prognostic Factors in Axillary Node-Negative Breast Cancer… 
1989
1989
Activated oncogenes in human skin tumors from a repair-deficient syndrome, xeroderma pigmentosum.
The recessive autosomal hereditary disease, xeroderma pigmentosum (XP), is characterized by a high incidence of tumors in sun… 
1987
1987
Mapping of the oncogenes Myc, Sis, and int-1 to the distal part of mouse chromosome 15.
Two proto-oncogenes, Myc and Sis, as well as a putative mouse oncogene, int-1, were localized by in situ hybridization to the… 
1987
1987
Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.
Temperature-sensitive protein-tyrosine kinase (EC 2.7.1.112) mutants of the oncogene v-abl have been obtained by a direct… 
1986
1986
Growth factors, oncogenes and inositol lipids.
: Normal cells require growth factors to multiply. One group of growth factors such as platelet-derived growth factor, bombesin… 
1986
1986
Expression of monocyte-specific oncogenes c-fos and c-fms in HL60 cells treated with vitamin D3 analogs correlates with inhibition of DNA synthesis and reduced calmodulin concentration.
Monocytic differentiation of cultured leukemic cells HL60 can be induced by a variety of compounds including analogs of vitamin… 
Review
1985
Review
1985
NIH conference. Molecular genetic analysis of human lymphoid neoplasms. Immunoglobulin genes and the c-myc oncogene.
Immunoglobulin genes responsible for individual antibodies are organized as discontinuous DNA segments in their germline form. As… 
1985
1985
Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
The presence of activated oncogenes in several rat hepatocellular carcinomas induced by 2-amino-3-methylimidazo[4,5-f]-quinoline… 
Review
1981
Review
1981
Retroviral gene expression.
Retroviruses1 have been extensively studied during the past 10–20 years. These viruses are of particular interest to molecular…