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Oncogenes
Known as:
Oncogene
, Cancer-Promoting Gene
, Genes, Transforming
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Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of…
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National Institutes of Health
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Related topics
Related topics
48 relations
BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I
CCDC6/RET Fusion Protein
Cancer Promoting Genes
Carcinogens
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Narrower (11)
FOS Family Genes
MYC Family Genes
REL gene
SRC gene
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Broader (2)
Genes
Mutation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Oncogenes and cancer.
C. Croce
New England Journal of Medicine
2008
Corpus ID: 8813076
This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor…
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Highly Cited
2005
Highly Cited
2005
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.
E. Weisberg
,
P. Manley
,
+19 authors
J. Griffin
Cancer Cell
2005
Corpus ID: 27582661
Highly Cited
1999
Highly Cited
1999
PIK3CA is implicated as an oncogene in ovarian cancer
Laleh Shayesteh
,
Yiling Lu
,
+7 authors
J. Gray
Nature Genetics
1999
Corpus ID: 1108912
Ovarian cancer is the leading cause of death from gynecological malignancy and the fourth leading cause of cancer death among…
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Review
1998
Review
1998
The HER‐2/neu Oncogene in Breast Cancer: Prognostic Factor, Predictive Factor, and Target for Therapy
J. Ross
,
J. Fletcher
Stem Cells
1998
Corpus ID: 542820
The HER‐2/neu oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the epidermal growth factor…
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Highly Cited
1990
Highly Cited
1990
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.
T. Lugo
,
A. Pendergast
,
A. Muller
,
O. Witte
Science
1990
Corpus ID: 26670919
Oncogenic activation of the proto-oncogene c-abl in human leukemias occurs as a result of the addition of exons from the gene bcr…
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Highly Cited
1987
Highly Cited
1987
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
K. Forrester
,
C. Almoguera
,
Kyuhyung Han
,
W. Grizzle
,
M. Perucho
Nature
1987
Corpus ID: 21444633
RNAse A mismatch cleavage analysis of 66 primary human colon tumours reveals a high incidence of K-ras genes with mutations at…
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Review
1983
Review
1983
Cellular oncogenes and retroviruses.
J. Bishop
Annual Review of Biochemistry
1983
Corpus ID: 11530984
Devoilement des oncogenes cellulaires: strategies experimentales et definitions. Caracteristiques structurales. Phylogenese…
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Review
1983
Review
1983
Cellular oncogenes and multistep carcinogenesis.
H. Land
,
L. Parada
,
R. Weinberg
Science
1983
Corpus ID: 22660092
Two dozen cellular proto-oncogenes have been discovered to date through the study of retroviruses and the use of gene transfer…
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Highly Cited
1983
Highly Cited
1983
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
M. Schwab
,
K. Alitalo
,
+6 authors
J. Trent
Nature
1983
Corpus ID: 4268700
Amplified cellular genes in mammalian cells frequently manifest themselves as double minute chromosomes (DMs) and homogeneously…
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Highly Cited
1982
Highly Cited
1982
Mechanism of activation of a human oncogene
C. Tabin
,
S. Bradley
,
+6 authors
E. Chang
Nature
1982
Corpus ID: 4253259
The oncogene of the human EJ bladder carcinoma cell lines arose via alteration of a cellular proto-oncogene. Experiments are…
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