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Oncogenes

Known as: Oncogene, Cancer-Promoting Gene, Genes, Transforming 
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Background: Cancer is one of the major heterogeneous disease with high morbidity and mortality with poor prognosis. Elevated… Expand
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Review
2018
Review
2018
DISEASE OVERVIEW Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with an incidence of 1-2 cases per 100 000… Expand
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Review
2018
Review
2018
The MYC family oncogene is deregulated in >50% of human cancers, and this deregulation is frequently associated with poor… Expand
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Review
2018
Review
2018
Oncogene activation disturbs cellular processes and accommodates a complex landscape of changes in the genome that contribute to… Expand
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Review
2018
Review
2018
The Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. It is a highly conserved evolutionary pathway… Expand
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Review
2018
Review
2018
Purpose Approximately 1% to 2% of non-small-cell lung cancers (NSCLCs) harbor a c-ros oncogene 1 ( ROS1) rearrangement… Expand
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Review
2018
Review
2018
Hepatocellular carcinoma (HCC) is a leading lethal malignancy worldwide. However, the molecular mechanisms underlying liver… Expand
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Review
2018
Review
2018
Thyroid cancer continues to be the most common malignancy of endocrine glands. The incidence of thyroid cancer has risen… Expand
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Review
2017
Review
2017
The unfolded protein response (UPR) is an adaptive cellular program used by eukaryotic cells to cope with protein misfolding… Expand
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Review
2017
Review
2017
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately linked to epithelial… Expand
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