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Cancer Promoting Genes

Known as: Cancer Gene, Cancer Genes, Cancer-Promoting Gene 
Normal genes, that when altered or inappropriately expressed, contribute to malignant transformation, tumor progression, or metastasis.
National Institutes of Health

Related topics

Related topics

32 relations
ANP32C protein, humanB Melanoma Antigen 1BCAS1 protein, humanBCAS3 Protein

Broader (1)

Genes, Neoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs
Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However… 
2017
2017
A novel molecular diagnostics platform for somatic and germline precision oncology
Next‐generation sequencing (NGS) opens new options in clinical oncology, from therapy selection to genetic counseling. However… 
2015
2015
Genome analysis Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data
Motivation: Several tools exist to identify cancer driver genes based on somatic mutation data. However, these tools do not… 
2013
2013
Clonal Expansion Analysis of Transposon Insertions by High-Throughput Sequencing Identifies Candidate Cancer Genes in a PiggyBac Mutagenesis Screen
Somatic transposon mutagenesis in mice is an efficient strategy to investigate the genetic mechanisms of tumorigenesis. The… 
2013
2013
Genes Dysregulated to Different Extent or Oppositely in Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancers
Background Directly comparing gene expression profiles of estrogen receptor-positive (ER+) and estrogen receptor-negative (ER… 
2012
2012
Identification of retinoblastoma related genes with shortest path in a protein-protein interaction network.
Review
2006
Review
2006
The Cancer Genome and Diagnostic Blood Tests
According to dogma in the information era of biomedicine, more DNA sequencing and protein profiling will inevitably lead to… 
Review
2005
Review
2005
Using Comparative Genomics to Leverage Animal Models in the Identification of Cancer Genes. Examples in Prostate Cancer.
The identification of cancer biomarkers that will predict susceptibility to disease and subsequent clinical outcome are key… 
1999
1999
A bumper crop of cancer genes
Although genetics can provide an insight into the underpinnings of a biological process, it typically does so one gene at a time… 
Review
1986
Review
1986
Somatic events unmask recessive cancer genes to initiate malignancy
A heritable mutation predisposes an individual to certain childhood malignancies, such as retinoblastoma and Wilms' tumor. The… 
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