REL gene

Known as: v-rel Genes, v rel Oncogenes, V-REL AVIAN RETICULOENDOTHELIOSIS VIRAL ONCOGENE HOMOLOG 
This gene is involved in transcriptional regulation and signal transduction through the nuclear factor kappa B NFKB signal transduction pathway.

Topic mentions per year

Topic mentions per year

1969-2018
0204019692018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Regulatory T (Treg) cells are essential for maintaining immune homeostasis. Although Foxp3 expression marks the commitment of… (More)
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Highly Cited
2009
Highly Cited
2009
We conducted a genome-wide association study of rheumatoid arthritis in 2,418 cases and 4,504 controls from North America and… (More)
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Highly Cited
2005
Highly Cited
2005
We consider three approaches for estimating the rates of nonsynonymous and synonymous changes at each site in a sequence… (More)
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Highly Cited
2003
Highly Cited
2003
Structural aberrations of the short arm of chromosome 2, mostly resulting in gains of 2p13 approximately 16, have recently been… (More)
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Highly Cited
2001
Highly Cited
2001
Interleukin 12 (IL-12) is a 70-kD proinflammatory cytokine produced by antigen presenting cells that is essential for the… (More)
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Highly Cited
2000
Highly Cited
2000
The transcription factors of the Rel/NF-kappaB family are key regulators of immune and inflammatory responses and contribute to… (More)
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Highly Cited
2000
Highly Cited
2000
A major challenge in the study of gene regulation by NF-kappaB/Rel transcription factors is to understand, at the biological and… (More)
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Highly Cited
1997
Highly Cited
1997
Human monocyte chemoattractant protein-1 (human MCP-1) mRNA accumulated in THP-1 cells 2 h after lipopolysaccharide (LPS… (More)
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Highly Cited
1992
Highly Cited
1992
Analysis of the p50 and p65 subunits of the NF-kappa B transcription factor complex has revealed that both proteins can interact… (More)
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Highly Cited
1992
Highly Cited
1992
NF-kappa B is an inducible transcription factor comprised of a 50-kD (p50) and a 65-kD (p65) subunit. Induction of NF-kappa B… (More)
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