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MYC Family Genes

Known as: MYC Family Gene, MYC Gene, Gene, myc 
MYC Family Genes encode MYC Family Proteins, class III bHLH leucine zipper transcription factors having cellular proliferative and apoptotic roles… Expand
National Institutes of Health

Related topics

Related topics

11 relations
Homo sapiensMYC Family ProteinOncogene Protein p55(v-myc)Proto-Oncogene Proteins c-myc
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Narrower (2)

MYC genec-myc Genes

Broader (1)

Oncogenes

Papers overview

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Highly Cited
2006
Highly Cited
2006
CTCF-dependent chromatin insulator is linked to epigenetic remodeling.
Chromatin insulators are boundary elements between distinctly regulated, neighboring chromosomal domains, and they function by… Expand
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Highly Cited
1998
Highly Cited
1998
Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis
The gfi-1 gene encodes a zinc finger containing protein that is specifically expressed in T-lymphocytes and is a frequent target… Expand
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1998
1998
The immunoglobulin heavy chain locus control region increases histone acetylation along linked c-myc genes.
In chromosome translocations characteristic of Burkitt lymphomas (BL) and murine plasmacytomas, c-myc genes become juxtaposed to… Expand
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Highly Cited
1996
Highly Cited
1996
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.
We have isolated and analyzed human CTCF cDNA clones and show here that the ubiquitously expressed 11-zinc-finger factor CTCF is… Expand
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Review
1991
Review
1991
Control of c-myc regulation in normal and neoplastic cells.
Publisher Summary This chapter discusses normal c -myc gene regulation and abnormal c- myc regulation in cancer cells. All normal… Expand
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Highly Cited
1990
Highly Cited
1990
Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours
THE recent finding of c-myc activation by insertion of woodchuck hepatitis virus DNA in two independent hepatocellular carcinoma1… Expand
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Highly Cited
1986
Highly Cited
1986
Differential expression of myc family genes during murine development
The myc family of cellular oncogenes contains three known members. The N-myc and c-myc genes have 5′-noncoding exons, strikingly… Expand
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Highly Cited
1985
Highly Cited
1985
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer
Altered structure and regulation of the c-myc proto-oncogene have been associated with a variety of human tumours and derivative… Expand
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Highly Cited
1983
Highly Cited
1983
Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
The 15;12 chromosome translocation in murine plasmacytomas and the 8;14 in human Burkitt lymphomas often link the cellular myc… Expand
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Highly Cited
1982
Highly Cited
1982
Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas
We have found that the myc oncogene has been modified by abortive recombination with the alpha heavy-chain immunoglobulin… Expand
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