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MYC Family Genes

Known as: MYC Family Gene, MYC Gene, Gene, myc 
MYC Family Genes encode MYC Family Proteins, class III bHLH leucine zipper transcription factors having cellular proliferative and apoptotic roles… Expand
National Institutes of Health

Related topics

Related topics

11 relations
Homo sapiensMYC Family ProteinOncogene Protein p55(v-myc)Proto-Oncogene Proteins c-myc
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Narrower (2)

MYC genec-myc Genes

Broader (1)

Oncogenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
CTCF-dependent chromatin insulator is linked to epigenetic remodeling.
Chromatin insulators are boundary elements between distinctly regulated, neighboring chromosomal domains, and they function by… Expand
Highly Cited
1996
Highly Cited
1996
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.
We have isolated and analyzed human CTCF cDNA clones and show here that the ubiquitously expressed 11-zinc-finger factor CTCF is… Expand
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Review
1991
Review
1991
Control of c-myc regulation in normal and neoplastic cells.
Publisher Summary This chapter discusses normal c-myc gene regulation and abnormal c-myc regulation in cancer cells. All normal c… Expand
Highly Cited
1990
Highly Cited
1990
Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours
THE recent finding of c-myc activation by insertion of woodchuck hepatitis virus DNA in two independent hepatocellular carcinoma1… Expand
Highly Cited
1986
Highly Cited
1986
Differential expression of myc family genes during murine development
The myc family of cellular oncogenes contains three known members. The N-myc and c-myc genes have 5′-noncoding exons, strikingly… Expand
Highly Cited
1985
Highly Cited
1985
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer
Altered structure and regulation of the c-myc proto-oncogene have been associated with a variety of human tumours and derivative… Expand
Highly Cited
1984
Highly Cited
1984
Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma
Our previous studies of a translocated c-myc gene in the Raji Burkitt's lymphoma cell showed somatic mutations in exons 1 and 2… Expand
Highly Cited
1984
Highly Cited
1984
Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
  • D. Tuan, I. London
  • Proceedings of the National Academy of Sciences…
  • 1984
    • Corpus ID: 2259377
We have mapped the DNase I-hypersensitive sites around the epsilon-globin and c-myc genes in two human leukemia cell lines K562… Expand
Highly Cited
1983
Highly Cited
1983
Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
The 15;12 chromosome translocation in murine plasmacytomas and the 8;14 in human Burkitt lymphomas often link the cellular myc… Expand
Highly Cited
1982
Highly Cited
1982
Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas
We have found that the myc oncogene has been modified by abortive recombination with the alpha heavy-chain immunoglobulin… Expand
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