Proto-Oncogene Proteins c-myc

Known as: myc, Proto-Oncogene Proteins, Proteins myc, Proto-Oncogene, Proto-Oncogene Proteins c-myc [Chemical/Ingredient] 
Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism, and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
MYC contributes to the pathogenesis of a majority of human cancers, yet strategies to modulate the function of the c-Myc… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Altered glucose metabolism in cancer cells is termed the Warburg effect, which describes the propensity of most cancer cells to… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The c-Myc oncogenic transcription factor (Myc) is pathologically activated in many human malignancies. Myc is known to directly… (More)
Is this relevant?
Review
2008
Review
2008
Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are 21–23 nucleotide RNA molecules that regulate the stability or translational efficiency of target messenger… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2002
Review
2002
Deregulated expression of c-MYC occurs in a broad range of human cancers and is often associated with poor prognosis, indicating… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2002
Review
2002
The proto-oncogene c-myc has been shown to play a pivotal role in cell cycle regulation, metabolism, apoptosis, differentiation… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The MYC proto-oncogene encodes a ubiquitous transcription factor (c–MYC) involved in the control of cell proliferation and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The adenomatous polyposis coli gene (APC) is a tumor suppressor gene that is inactivated in most colorectal cancers. Mutations of… (More)
Is this relevant?