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MYC gene

Known as: Oncogene, myc, myc Oncogene, bHLHe39 
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are… 
National Institutes of Health

Related topics

Related topics

49 relations
8q24.12-q24.13AIDS-Related Cervical CarcinomaBurkitt LymphomaBurkitt Lymphoma with Plasmacytoid Differentiation

Broader (1)

MYC Family Genes

Narrower (1)

MYC wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Regulation of c-Myc through Phosphorylation at Ser-62 and Ser-71 by c-Jun N-Terminal Kinase*
The expression of c-myc promotes cell proliferation and also sensitizes cells to various extracellular apoptotic stimuli. However… 
Highly Cited
1996
Highly Cited
1996
c-Myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways.
Enforced c-Myc expression promotes inappropriate cell cycle progression of growth factor deprived cells and triggers concomitant… 
Highly Cited
1994
Highly Cited
1994
Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma.
The MRP gene (Cole et al., Science (Washington DC), 258: 1650-1654, 1992) encodes a membrane-bound glycoprotein the expression of… 
Highly Cited
1994
Highly Cited
1994
Lymphoma models for B cell activation and tolerance. X. Anti-mu- mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc
Treatment of the WEHI-2131 or CH31 B cell lymphomas with anti-mu or transforming growth factor (TGF)-beta leads to growth… 
Highly Cited
1993
Highly Cited
1993
Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.
c-Myc and Max are nuclear phosphoproteins capable of forming DNA-binding, homo- and heteropolymeric complexes in vitro and in… 
Highly Cited
1992
Highly Cited
1992
An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence.
We have used a subtraction/coexpression strategy involving two different tumors derived from c-myc-bearing transgenic mice to… 
Highly Cited
1987
Highly Cited
1987
High correlation between molecular alterations of the c-myc oncogene and carcinoma of the uterine cervix.
We have examined 35 human tumors of the uterine cervix (carcinoma presenting the highest incidence in Mexico; about 34% of women… 
Highly Cited
1985
Highly Cited
1985
Nonrandom loss of chromosome 15 in Syrian hamster tumours induced by v-Ha-ras plus v-myc oncogenes
Nonrandom chromosome rearrangements, observed in a variety of human and animal tumours1,2, are associated in some cases with… 
Highly Cited
1985
Highly Cited
1985
Rapid induction of hemopoietic neoplasms in newborn mice by a raf(mil)/myc recombinant murine retrovirus
3611 MSV, a raf oncogene-transducing murine retrovirus, induced fibrosarcomas in newborn mice after a latency of 4 to 8 weeks. In… 
Highly Cited
1983
Highly Cited
1983
Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt.
We have studied somatic cell hybrids between mouse myeloma cells and IARC-BL2 Burkitt lymphoma human cells carrying a t(8;22… 
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