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MYC gene

Known as: Oncogene, myc, myc Oncogene, bHLHe39 
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The MYC family oncogene is deregulated in >50% of human cancers, and this deregulation is frequently associated with poor… Expand
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Highly Cited
2012
Highly Cited
2012
Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression… Expand
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Review
2006
Review
2006
For more than a decade, numerous studies have suggested that the c-Myc oncogenic protein is likely to broadly influence the… Expand
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Highly Cited
2005
Highly Cited
2005
To date, more than 200 microRNAs have been described in humans; however, the precise functions of these regulatory, non-coding… Expand
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Highly Cited
2004
Highly Cited
2004
The stability of c-Myc is regulated by multiple Ras effector pathways. Phosphorylation at Ser 62 stabilizes c-Myc, whereas… Expand
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Highly Cited
1999
Highly Cited
1999
The targeted repair of mutant protooncogenes or the inactivation of their gene products may be a specific and effective therapy… Expand
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Highly Cited
1998
Highly Cited
1998
The adenomatous polyposis coli gene (APC) is a tumor suppressor gene that is inactivated in most colorectal cancers. Mutations of… Expand
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Highly Cited
1992
Highly Cited
1992
Although Rat-1 fibroblasts expressing c-myc constitutively are unable to arrest growth in low serum, their numbers do not… Expand
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Highly Cited
1985
Highly Cited
1985
Eighty-nine patients with untreated primary neuroblastomas were studied to determine the relation between the number of copies of… Expand
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Highly Cited
1985
Highly Cited
1985
Transgenic mice bearing the cellular myc oncogene coupled to the immunoglobulin μ or κ enhancer frequently develop a fatal… Expand
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