MYC gene

Known as: Oncogene, myc, myc Oncogene, bHLHe39 
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are… (More)

Topic mentions per year

Topic mentions per year

1979-2018
010020030019792018

Papers overview

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Highly Cited
2011
Highly Cited
2011
The MYC transcription factor is a master regulator of diverse cellular functions and has been long considered a compelling… (More)
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Highly Cited
2009
Highly Cited
2009
Approximately 5% to 10% of diffuse large B-cell lymphomas (DLBCLs) harbor an MYC oncogene rearrangement (MYC+). The prognostic… (More)
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Highly Cited
2009
Highly Cited
2009
An inherited variant on chromosome 8q24, rs6983267, is significantly associated with cancer pathogenesis. We present evidence… (More)
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Highly Cited
2007
Highly Cited
2007
Regulation of the MYC oncogene remains unclear. Using 10058-F4, a compound that inhibits MYC-MAX transcription factor, MYC… (More)
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Highly Cited
2005
Highly Cited
2005
Although several genes involved in mitochondrial function are direct Myc targets, the role of Myc in mitochondrial biogenesis has… (More)
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Highly Cited
2005
Highly Cited
2005
Cellular phenotypes are determined by the differential activity of networks linking coregulated genes. Available methods for the… (More)
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Highly Cited
2000
Highly Cited
2000
The prototypic oncogene c-MYC encodes a transcription factor that can drive proliferation by promoting cell-cycle reentry… (More)
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Highly Cited
1999
Highly Cited
1999
The MYC proto-oncogene encodes a ubiquitous transcription factor (c–MYC) involved in the control of cell proliferation and… (More)
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Highly Cited
1999
Highly Cited
1999
MYC gene overexpression was identified recently as a downstream step at the end of the Wnt/APC/beta-catenin pathway dysregulation… (More)
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Highly Cited
1991
Highly Cited
1991
The proto-oncogene MYC encodes a nuclear protein whose biochemical and physiological functions remain uncertain. We used an… (More)
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