MYC wt Allele

Known as: C-MYC, v-MYC Myelocytomatosis Viral Oncogene Homolog (Avian) wt Allele, v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog 
Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes myc proto-oncogene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
020040019562016

Papers overview

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Highly Cited
2012
Highly Cited
2012
Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression… (More)
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Highly Cited
2010
Highly Cited
2010
Recruitment of the RNA polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA-binding… (More)
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Highly Cited
2009
Highly Cited
2009
Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4 and Sox2) is sufficient to reprogram somatic… (More)
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Highly Cited
2007
Highly Cited
2007
The c-Myc proto-oncogene encodes a transcription factor that is essential for cell growth and proliferation and is broadly… (More)
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Highly Cited
2007
Highly Cited
2007
The APC gene encodes the adenomatous polyposis coli tumour suppressor protein, germline mutation of which characterizes familial… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are 21–23 nucleotide RNA molecules that regulate the stability or translational efficiency of target messenger… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms of cell proliferation and transformation are intrinsically linked to the process of apoptosis: the default of… (More)
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Highly Cited
1992
Highly Cited
1992
Although Rat-1 fibroblasts expressing c-myc constitutively are unable to arrest growth in low serum, their numbers do not… (More)
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Highly Cited
1985
Highly Cited
1985
Six monoclonal antibodies have been isolated from mice immunized with synthetic peptide immunogens whose sequences are derived… (More)
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Highly Cited
1985
Highly Cited
1985
Transgenic mice bearing the cellular myc oncogene coupled to the immunoglobulin μ or κ enhancer frequently develop a fatal… (More)
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