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MYC wt Allele
Known as:
C-MYC
, v-MYC Myelocytomatosis Viral Oncogene Homolog (Avian) wt Allele
, v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog
Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes myc proto-oncogene…
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National Institutes of Health
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Related topics
Related topics
27 relations
8q24.12-q24.13
Burkitt Lymphoma
CTCF Pathway
Cardiac Hypertrophy Pathway
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Broader (1)
MYC gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
iPS cells can support full-term development of tetraploid blastocyst-complemented embryos.
Lan Kang
,
Jianle Wang
,
Yu Zhang
,
Zhaohui Kou
,
Shaorong Gao
Cell Stem Cell
2009
Corpus ID: 16251634
Highly Cited
2004
Highly Cited
2004
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
A. Ramiro
,
M. Jankovic
,
+6 authors
M. Nussenzweig
Cell
2004
Corpus ID: 18714759
Highly Cited
1993
Highly Cited
1993
Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.
E. Postel
,
SJ Berberich
,
SJ Flint
,
C. Ferrone
Science
1993
Corpus ID: 43134409
A human gene encoding the c-myc purine-binding transcription factor PuF was identified by screening of a cervical carcinoma cell…
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Highly Cited
1991
Highly Cited
1991
An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro
G. Brewer
Molecular and Cellular Biology
1991
Corpus ID: 42082868
Transient expression of some proto-oncogenes, cytokines, and transcription factors occurs as a cellular response to growth…
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Highly Cited
1990
Highly Cited
1990
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.
J. Pietenpol
,
J. Holt
,
R. Stein
,
H. Moses
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 11839368
Transforming growth factor beta 1 (TGF-beta 1) is a potent growth inhibitor for many cell types, including most epithelial cells…
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Highly Cited
1989
Highly Cited
1989
A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.
D. Edmondson
,
E. Olson
Genes & Development
1989
Corpus ID: 24621139
MyoD1 is a nuclear phosphoprotein that is expressed in skeletal muscle in vivo and in certain muscle cell lines in vitro; it has…
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Highly Cited
1988
Highly Cited
1988
Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro.
M. Cooney
,
G. Czernuszewicz
,
E. Postel
,
S. J. Flint
,
M. Hogan
,
M. Hogan
Science
1988
Corpus ID: 13508218
A 27-base-long DNA oligonucleotide was designed that binds to duplex DNA at a single site within the 5' end of the human c-myc…
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Highly Cited
1988
Highly Cited
1988
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation
J. Holt
,
R. Redner
,
A. Nienhuis
,
A. Nienhuis
Molecular and Cellular Biology
1988
Corpus ID: 25418092
To study the role of a nuclear proto-oncogene in the regulation of cell growth and differentiation, we inhibited HL-60 c-myc…
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Highly Cited
1986
Highly Cited
1986
Differential expression of myc family genes during murine development
K. Zimmerman
,
G. Yancopoulos
,
+9 authors
F. Alt
Nature
1986
Corpus ID: 4350171
The myc family of cellular oncogenes contains three known members. The N-myc and c-myc genes have 5′-noncoding exons, strikingly…
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Highly Cited
1983
Highly Cited
1983
Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite
Pieter H. Reitsma
,
Paul G. Rothberg
,
+5 authors
Arnold J. Kahn
Nature
1983
Corpus ID: 4316265
HL-60, a cell line established from a patient with promyelocytic leukaemia, responds to a variety of inducing agents by ceasing…
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