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MYC wt Allele

Known as: C-MYC, v-MYC Myelocytomatosis Viral Oncogene Homolog (Avian) wt Allele, v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog 
Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes myc proto-oncogene… 
National Institutes of Health

Related topics

Related topics

27 relations
8q24.12-q24.13Burkitt LymphomaCTCF PathwayCardiac Hypertrophy Pathway

Broader (1)

MYC gene

Papers overview

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Highly Cited
1992
Highly Cited
1992
Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion.
The molecular basis of myocardial adaptation to ischemia and reperfusion is poorly understood. It is thought that nuclear proto… 
Highly Cited
1992
Highly Cited
1992
Biochemical characterization of programmed cell death in NGF-deprived sympathetic neurons.
Young sympathetic neurons die when deprived of nerve growth factor (NGF). Under such circumstances, cell death is appropriate to… 
Highly Cited
1992
Highly Cited
1992
An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence.
We have used a subtraction/coexpression strategy involving two different tumors derived from c-myc-bearing transgenic mice to… 
Highly Cited
1991
Highly Cited
1991
Binding of triple helix forming oligonucleotides to sites in gene promoters.
A class of triplex-forming oligodeoxyribonucleotides (TFOs) is described that can bind to naturally occurring sites in duplex DNA… 
Highly Cited
1989
Highly Cited
1989
Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein
c-Myc plays a part in the regulation of important cellular processes such as growth, differentiation and neoplastic… 
Highly Cited
1988
Highly Cited
1988
c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells
Friend murine erythroleukemia (F-MEL) cells were transfected with a plasmid bearing tandemly arranged mouse c-myc antisense and… 
Review
1985
Review
1985
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
The N-myc gene, which is distantly related to the proto-oncogene c-myc, was first detected as an amplified sequence in human… 
Highly Cited
1985
Highly Cited
1985
Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes
Several oncogenes are thought to cause transformation by affecting the signal transmission pathway of growth factors. One example… 
Highly Cited
1984
Highly Cited
1984
Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas.
Sixty-one murine leukemia virus-induced lymphomas were examined for evidence of proviral insertions adjacent to known oncogenes… 
Highly Cited
1984
Highly Cited
1984
Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomas.
We induced AKR thymomas by injecting retrovirus MCF 247 that we had tagged with a fragment of phage lambda in its U3 region… 
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