Skip to search formSkip to main contentSkip to account menu

Oncogene Activation Process

Known as: Oncogene Activation 
Any DNA sequence alteration process occurring in a proto-oncogene, resulting in loss of regulation of the gene product, and predisposing the cell to… 
National Institutes of Health

Related topics

Related topics

1 relation
Neoplastic Cell Transformation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
p53 Protein Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression*
Background: The mechanism by which p53, a tumor suppressor gene, regulates Wnt signaling is incompletely understood. Results: p53… 
Highly Cited
2013
Highly Cited
2013
Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment
Here, we developed a model system to evaluate the metabolic effects of oncogene(s) on the host microenvironment. A matched set of… 
1996
1996
Ret and trk proto-oncogene activation in thyroid papillary carcinomas in French patients from the Champagne-Ardenne region.
Highly Cited
1994
Highly Cited
1994
Molecular characterization of CD30+ anaplastic large-cell lymphoma: high frequency of c-myc proto-oncogene activation.
Anaplastic large-cell lymphoma (ALCL) represents a morphologically distinct type of non-Hodgkin's lymphoma (NHL) characterized… 
1993
1993
Timing of SV40 oncogene activation by site-specific recombination determines subsequent tumor progression during murine lens development.
We generated mice that carry copies of a dormant transgene encoding the SV40 tumor antigens. The transgenes are specifically… 
Highly Cited
1993
Highly Cited
1993
Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride.
Methylene chloride has been the subject of recent toxicological and carcinogenesis studies because of significant human exposure… 
1990
1990
Spi-1 oncogene activation in Rauscher and Friend murine virus-induced acute erythroleukemias.
The Friend viruses, like the Rauscher virus, cause murine acute erythroleukemias which evolve in a similar multistep process. In… 
Highly Cited
1988
Highly Cited
1988
ras oncogene activation in human ovarian carcinoma.
Samples of 37 fresh human ovarian tumor biopsies were screened to detect proto-oncogene amplification and ras mutations. Three… 
Highly Cited
1987
Highly Cited
1987
Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation.
The c-abl gene codes for a protein-tyrosine kinase and is expressed in most examined murine cell types as two distinct mRNA… 
1984
1984
Mouse c-mos oncogene activation is prevented by upstream sequences.
Although the molecularly cloned mouse c-mos oncogene locus can be efficiently activated by insertion of a retroviral long… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)