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Oncogene Activation Process

Known as: Oncogene Activation 
Any DNA sequence alteration process occurring in a proto-oncogene, resulting in loss of regulation of the gene product, and predisposing the cell to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2016
012319912016

Related topics

Related topics

1 relation
Neoplastic Cell Transformation

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
Oncogene Activation Process
Neoplastic Cell Transformation

Papers overview

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2017
2017
Mechanisms of Oncogene Activation
The main modifications that characterize cancer are represented by alterations in onco‐ genes, tumor-suppressor genes, and non… (More)
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2016
2016
RNF4-Dependent Oncogene Activation by Protein Stabilization
Ubiquitylation regulates signaling pathways critical for cancer development and, in many cases, targets proteins for degradation… (More)
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2016
2016
Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes
Insertional oncogenesis due to retroviral (RV) vector integration has caused recurrent leukemia in multiple gene therapy trials… (More)
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2016
2016
Isocitrate Dehydrogenase Mutation Leads to Alteration in 3-Dimensional DNA Structure and Oncogene Activation in Gliomas.
shown that increased frequency of stimulation increased the efficacy ofmuscle fiber recruitment but did not alter the temporal… (More)
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2011
2011
Oncogene Activation Induces Metabolic Transformation Resulting in Insulin-Independence in Human Breast Cancer Cells
Normal breast epithelial cells require insulin and EGF for growth in serum-free media. We previously demonstrated that over… (More)
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2006
2006
Correlation of Thyroid Hormone Dose-dependent Regulation of K-ras Proto oncogene Expression with Oncogene Activation by 3-Methylcholanthrene: Loss of Thyroidal Regulation in the Transformed Mouse…
Previously, it has been demonstrated that thyroid hormone is an important cofactor of the initiation of oncogenesis in viro and… (More)
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2006
2006
Oncogene Activation and Tumor Suppressor Gene Inactivation during Multistage Mouse Skin Carcinogenesis1
The mouse skin multistage model of carcinogenesis is an ideal system in which to study questions related to the timing of… (More)
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Review
2004
Review
2004
Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species.
Oligodeoxyribonucleotides containing 8-hydroxyguanine and 2-hydroxyadenine, purine lesions produced in cells by reactive oxygen… (More)
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2000
2000
TCLl Oncogene Activation in Preleukemic T Cells
The TCLI oncogene on human chromosome 14q32.1 is involved in chromosome translocations [t(14;14)(qll;q32.1) and t(7;14)(q35;q32.1… (More)
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1991
1991
Retroviral Insertion and Oncogene Activation
 
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