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Nortriptyline

Known as: NTPL, Desmethylamitriptyline, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl- 
A tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (10)

10-hydroxynortriptyline10-oxonortriptylineAventylMotipress

Broader (5)

Adrenergic Uptake InhibitorsAntidepressive AgentsDibenzocycloheptenesTricyclic Antidepressive Agents
Affective Disorders, PsychoticAmitriptylineAmitriptyline Hydrochloride 50 MG Oral TabletAnxiety Disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Kinetic aspects of hollow fiber liquid-phase microextraction and electromembrane extraction.
Highly Cited
2007
Highly Cited
2007
White Matter Axon Vulnerability to AMPA/Kainate Receptor-Mediated Ischemic Injury Is Developmentally Regulated
Periventricular white matter injury (PWMI) is the leading cause of neurodevelopmental morbidity in survivors of premature birth… 
Highly Cited
1999
Highly Cited
1999
Effectiveness of treatments for major depression in primary medical care practice: a post hoc analysis of outcomes for African American and white patients.
Highly Cited
1997
Highly Cited
1997
Solid-phase microextraction with capillary gas-liquid chromatography and nitrogen-phosphorus selective detection for the assay of antidepressant drugs in human plasma.
  • S. UlrichJ. Martens
  • Journal of Chromatography B: Biomedical Sciences…
  • 1997
  • Corpus ID: 23680969
Highly Cited
1985
Highly Cited
1985
Pharmacological interference with the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse.
Highly Cited
1975
Highly Cited
1975
First‐pass metabolism of nortriptyline in man
The kinetics of nortriptyline were studied after oral and intravenous (iv) administration of test doses of 50 mg 14C… 
Highly Cited
1974
Highly Cited
1974
Plasma nortriptyline and clinical response
The relationship of plasma nortriptyline levels to the clinical response of 80 depressed patients was studied. Plasma… 
Highly Cited
1972
Highly Cited
1972
Effect of apomorphine on motility in rats.
Highly Cited
1971
Highly Cited
1971
Genetic control of nortriptyline kinetics in man: a study of relatives of propositi with high plasma concentrations.
Considerable variability has been observed in the steady-state plasma concentrations of nortriptyline in psychiatric patients… 
Highly Cited
1969
Highly Cited
1969
Decreased turnover in central 5-HT nerve terminals induced by antidepressant drugs of the imipramine type.
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