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Nortriptyline

Known as: NTPL, Desmethylamitriptyline, 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl- 
A tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (10)

10-hydroxynortriptyline10-oxonortriptylineAventylMotipress

Broader (5)

Adrenergic Uptake InhibitorsAntidepressive AgentsDibenzocycloheptenesTricyclic Antidepressive Agents
Affective Disorders, PsychoticAmitriptylineAmitriptyline Hydrochloride 50 MG Oral TabletAnxiety Disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Novel method for the fast determination of ultra trace amount of nortriptyline in its pharmaceutical formulations by fast fourier transform continuous cyclic voltammetric technique at Au…
In this work a novel method for the determination of nortriptyline in flow-injection systems has been developed. The proposed… 
1986
1986
Quantitative homogeneous enzyme immunoassays for amitriptyline, nortriptyline, imipramine, and desipramine.
We describe specific EMIT homogeneous enzyme immunoassays for amitriptyline, nortriptyline, imipramine, and desipramine in… 
1985
1985
Dose and plasma levels of nortriptyline and chlorpromazine in delusionally depressed adolescents and of nortriptyline in nondelusionally depressed adolescents.
Eight adolescents with major depressive disorder were treated with nortriptyline and six adolescents with delusional depression… 
1983
1983
Contributions of two inducible forms of cytochrome P-450 in rat liver microsomes to the metabolic activation of various chemical carcinogens.
Using the liver 9000 × g supernatant fraction of uninduced rats and monospecific antibodies against microsomal reduced… 
1983
1983
Cimetidine's Effect on Steady-State Serum Nortriptyline Concentrations
A cimetidine-nortriptyline interaction in a 52-year-old black male is reported. After concomitant administration of cimetidine… 
1979
1979
Specific radioimmunoassay of amitriptyline and nortriptyline.
1 Antisera to nortriptyline were prepared by immunizing rabbits with N-succinylnortriptyline--bovine serum albumin conjugate. 2 A… 
1978
1978
A radioimmunoassay for nortriptyline (and other tricyclic antidepressants) in plasma.
The radioimmunoassay for nortriptyline described here can detect as little 1 microgram/liter of plasma. Within-day precision and… 
1976
1976
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents.
Synthesis of 1'-methyl-3-phenylspiro[isobenzofuran-1(3H),4'-piperidine] (7a, HP 365) and the demethyl analogue 9a (HP 505) was… 
1975
1975
Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline.
1 Hospitalized patients suffering from insomnia were treated with N-demethyldiazepam (30 mg p.o.) for 10 days, while continuing… 
1972
1972
Ophthalmological effects of nortriptyline--relationship to plasma level.
Amplitude of accommodation and pupillary size were measured before and during therapy with nortriptyline in 41 depressed in…