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10-hydroxynortriptyline

Known as: 10,11-dihydro-5-(3-(methylamino)propylidene)-5H- dibenzo(a,d)cyclohepten-10-ol 
National Institutes of Health

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2 relations

Broader (1)

Nortriptyline
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Plasma and brain pharmacokinetics of amitriptyline and its demethylated and hydroxylated metabolites after one and six half-life repeated administrations to rats.
1992
1992
Column switching and high-performance liquid chromatography in the analysis of amitriptyline, nortriptyline and hydroxylated metabolites in human plasma or serum.
1988
1988
Electrocardiographic changes with nortriptyline and 10-hydroxynortriptyline in elderly depressed outpatients.
Pharmacokinetic factors may contribute to altered nortriptyline effects in the elderly. Plasma concentrations of nortriptyline's… 
1987
1987
Clinical and biochemical effects during treatment of depression with nortriptyline: The role of 10‐hydroxynortriptyline
Plasma concentrations of nortriptyline (NT) and its major metabolite 10‐hydroxy‐NT (10‐OH‐NT) were measured in 30 patients with… 
1987
1987
Applications of column-switching technique in biopharmaceutical analysis. I. High-performance liquid chromatographic determination of amitriptyline and its metabolites in human plasma.
1985
1985
Plasma 10-hydroxynortriptyline and ECG changes in elderly depressed patients.
Among 18 elderly depressed patients given ECGs before and during nortriptyline treatment, plasma E-10-hydroxynortriptyline and… 
1984
1984
Plasma 10‐hydroxynortriptyline in elderly depressed patients
Plasma concentrations of nortriptyline (NT) and of unconjugated E‐10‐hydroxynortriptyline (E‐10‐OH‐NT) were measured under steady… 
1979
1979
A method for the determination of amitriptyline and its metabolites nortriptyline, 10‐hydroxyamitriptyline, and 10‐hydroxynortriptyline in human plasma using stable isotope dilution and gas…
A gas chromatography‐mass spectrometry (GC‐MS) method has been developed to measure amitriptyline and its metabolites… 
1976
1976
Nortriptyline and 10‐hydroxynortriptyline plasma concentrations
Nortriptyline is a frequently prescribed tricyclic antidepressant. Although the major nortriptyline metabolite in human… 
1972
1972
Plasma disappearance of nortriptyline in a newborn infant following placental transfer from an intoxicated mother: evidence for drug metabolism.
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