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Nomifensine

Known as: (R)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine, Nomifensin, 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl- 
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
We investigated the effects of chronic nicotine on α6- and β3-containing nicotinic acetylcholine receptors (nAChRs) in two rat… Expand
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Highly Cited
2000
Highly Cited
2000
Nicotinic agonists elicit the release of dopamine from striatal synaptosomes by acting on presynaptic nicotinic acetylcholine… Expand
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Review
1999
Review
1999
Intracranial self-administration (ICSA) and intracranial place conditioning (ICPC) methodologies have been mainly used to study… Expand
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Highly Cited
1997
Highly Cited
1997
Using radioligand binding assays, we determined the equilibrium dissociation constants (KD's) for 37 antidepressants, three of… Expand
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Highly Cited
1995
Highly Cited
1995
Whether amphetamine acts principally at the plasma membrane or at synaptic vesicles is controversial. We find that d-amphetamine… Expand
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Highly Cited
1995
Highly Cited
1995
The effects of cocaine and nomifensine on the uptake of dopamine have been compared in the caudate-putamen and nucleus accumbens… Expand
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Highly Cited
1991
Highly Cited
1991
1. Parallel series of experiments were carried out in the rat and mouse in order to investigate the mechanism(s) underlying the… Expand
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Highly Cited
1989
Highly Cited
1989
The effect of systemically administered amphetamine, cocaine, phencyclidine and nomifensine on the extracellular concentrations… Expand
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Highly Cited
1988
Highly Cited
1988
The rate of overflow and disappearance of dopamine from the extracellular fluid of the rat striatum has been measured during… Expand
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Highly Cited
1985
Highly Cited
1985
A novel test procedure for antidepressants was designed in which a mouse is suspended by the tail from a lever, the movements of… Expand
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