Nomifensine

Known as: (R)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine, Nomifensin, 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl- 
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
05010019732017

Papers overview

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Highly Cited
1997
Highly Cited
1997
Using radioligand binding assays, we determined the equilibrium dissociation constants (KD's) for 37 antidepressants, three of… (More)
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Highly Cited
1996
Highly Cited
1996
Rats learned to lever-press when such behavior was reinforced by microinjections of phencyclidine (PCP) directly into the… (More)
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Highly Cited
1995
Highly Cited
1995
Rats learned to lever-press when reinforced with response-contingent microinfusions of the dopamine uptake inhibitor nomifensine… (More)
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Highly Cited
1995
Highly Cited
1995
Whether amphetamine acts principally at the plasma membrane or at synaptic vesicles is controversial. We find that d-amphetamine… (More)
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Highly Cited
1992
Highly Cited
1992
We have screened a human substantia nigra cDNA library with probes derived from the rat dopamine transporter. A 3.5-kilobase cDNA… (More)
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Highly Cited
1991
Highly Cited
1991
1. Parallel series of experiments were carried out in the rat and mouse in order to investigate the mechanism(s) underlying the… (More)
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Highly Cited
1989
Highly Cited
1989
The effect of systemically administered amphetamine, cocaine, phencyclidine and nomifensine on the extracellular concentrations… (More)
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Highly Cited
1985
Highly Cited
1985
A novel test procedure for antidepressants was designed in which a mouse is suspended by the tail from a lever, the movements of… (More)
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1982
1982
Nomifensine and a proposed dihydroxy metabolite produced stimulation of motor behavior in mice with nomifensine being more potent… (More)
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Highly Cited
1978
Highly Cited
1978
The effects of pipradrol (5–15 mg/kg), methylphenidate (5–15 mg/kg), d-amphetamine (0.5–3.0 mg/kg), and nomifensine (5–15 mg/kg… (More)
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