Nalorphine

Known as: Allylnormorphine, Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)-, Nalorphine [Chemical/Ingredient] 
A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
010203019532017

Papers overview

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Highly Cited
1995
Highly Cited
1995
The ability of mu-opioid agonists to activate G proteins has been demonstrated by studying the binding of the GTP analogue… (More)
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1991
1991
Nalorphine is an unusual opiate. Whereas low doses of nalorphine antagonize morphine analgesia, higher nalorphine doses are… (More)
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1990
1990
The effects of several mixed-action opioid agonist/antagonists were examined alone and in combination with the mu-opioid agonist… (More)
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1983
1983
Nalorphine, butorphanol and oxilorphan were compared in their ability to increase urinary output in the normally hydrated rat and… (More)
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1977
1977
A randomized and blind experimental design was used to study the effects of naloxone and nalorphine on the development of… (More)
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Highly Cited
1976
Highly Cited
1976
A series of morphine-like and nalorphine-like drugs were studied in the nondependent, morphine-dependent and cyclazocine… (More)
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1970
1970
Every tenth lever-press of three morphine-dependent rhesus monkeys was reinforced with food. A red light, initially a neutral… (More)
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Highly Cited
1969
Highly Cited
1969
A method has been developed which permits monkeys to self-administer drug solutions, at will, through indwelling intravenous… (More)
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1969
1969
Three rhesus monkeys Macaca mulatta, formerly dependent on morphine, had increased sensitivity to nalorphine's effect of… (More)
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1967
1967
Three rhesus monkeys, physically dependent on morphine, were trained to press a lever for food on a fixed ratio of 10 responses… (More)
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