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Nalorphine

Known as: Allylnormorphine, Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)-, Nalorphine [Chemical/Ingredient] 
A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1976
Highly Cited
1976
A series of morphine-like and nalorphine-like drugs were studied in the nondependent, morphine-dependent and cyclazocine… Expand
Highly Cited
1975
Highly Cited
1975
1 Morphine inhibits the electrically evoked (0.1‐0.15 Hz, 1 ms) contractions of the longitudinal muscle of the mouse vas deferens… Expand
Highly Cited
1973
Highly Cited
1973
Naltrexone (EN-1639A) is approximately 17 times more potent than nalorphine as an antagonist in man. It is virtually devoid of… Expand
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Highly Cited
1971
Highly Cited
1971
Pharmacological properties of morphine-3-glucuronide and morphine-6-glucuronide were studied in mice and compared with those of… Expand
Highly Cited
1967
Highly Cited
1967
Secondary and tertiary alcohols of general structures IV and V have been prepared by the demethyla-tion of the corresponding… Expand
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Highly Cited
1959
Highly Cited
1959
Chronic administration of morphine and morphine-nalorphine mixtures to the rat results in a profound diminution of the analgesic… Expand
Highly Cited
1957
Highly Cited
1957
  • W. Paton
  • British journal of pharmacology and chemotherapy
  • 1957
  • Corpus ID: 31955055
Morphine depresses the twitch and tetanus of stimulated guinea‐pig ileum by reducing acetylcholine released from cholinergic… Expand
Highly Cited
1954
Highly Cited
1954
1. The analgesic efficacy and side action liability of nalorphine and nalorphinemorphine combinations have been studied in… Expand
Highly Cited
1952
Highly Cited
1952
  • A. Wikler
  • Proceedings of the Society for Experimental…
  • 1952
  • Corpus ID: 42174930
Summary 1. In unanesthetized, uncurarized dogs certain dose of morphine, N-allylnormorphine or atropine produce similar changes… Expand
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