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Nalorphine

Known as: Allylnormorphine, Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)-, Nalorphine [Chemical/Ingredient] 
A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
SummaryA method has been developed which permits monkeys to self-administer drug solutions, at will, through indwelling… Expand
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Highly Cited
1995
Highly Cited
1995
The ability of mu-opioid agonists to activate G proteins has been demonstrated by studying the binding of the GTP analogue… Expand
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Highly Cited
1976
Highly Cited
1976
A series of morphine-like and nalorphine-like drugs were studied in the nondependent, morphine-dependent and cyclazocine… Expand
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Highly Cited
1973
Highly Cited
1973
Naltrexone (EN-1639A) is approximately 17 times more potent than nalorphine as an antagonist in man. It is virtually devoid of… Expand
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1971
1971
Small doses of nalorphine (30-300 µg/kg) and naloxone (3-10 µg/kg) markedly increased the rate of i.v. morphine self… Expand
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Highly Cited
1959
Highly Cited
1959
Chronic administration of morphine and morphine-nalorphine mixtures to the rat results in a profound diminution of the analgesic… Expand
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1957
1957
  • V. L. Politi
  • Canadian Anaesthetists' Society journal
  • 1957
  • Corpus ID: 83544
SummaryStatistics still show that there has not been too great a reduction in the neonatal mortality from aetiological factors of… Expand
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1954
1954
1. The analgesic efficacy and side action liability of nalorphine and nalorphinemorphine combinations have been studied in… Expand
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1952
1952
  • Abraham Wikler
  • Proceedings of the Society for Experimental…
  • 1952
  • Corpus ID: 42174930
Summary 1. In unanesthetized, uncurarized dogs certain dose of morphine, N-allylnormorphine or atropine produce similar changes… Expand
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