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Smoking is the leading preventable cause of illness and premature death worldwide. Some medications have been proven… Expand Any medical treatment is surrounded by a psychosocial context that affects the therapeutic outcome. If we want to study this… Expand AIM
A 3-year update with 59 new controlled trials is provided for the ongoing Mesa Grande project reviewing clinical trials of… Expand We investigated the mechanisms underlying the activation of endogenous opioids in placebo analgesia by using the model of human… Expand The effects of the active ingredient of Cannabis, Delta9-tetrahydrocannabinol (Delta9-THC), and of the highly addictive drug… Expand Abstract Alcohol exerts numerous pharmacological effects through its interaction with various neurotransmitters and… Expand The localization of opiate receptors in the spinal cord and lower medulla has been elucidated by the autoradiographic… Expand Analgesia produced by focal electrical stimulation of the brain is partially reversed by the narcotic antagonist naloxone. The… Expand The endogenous morphinomimetic brain peptides Met5-enkephalin and alpha-, beta-, and gamma-endorphins have been evaluated in rats… Expand Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig… Expand