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Morphine

Known as: Morphia, (-)-morphine, Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)- 
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors… 
National Institutes of Health

Related topics

Related topics

44 relations
1 ML MORPHINE SULFATE LIPOSOMAL 10 MG/ML Injection [Depodur]10 ML Morphine Sulfate 1 MG/ML Injection [Duramorph]Codeine PhosphateIn Blood

Broader (4)

AlkaloidsAnalgesicsNarcotic AnalgesicsOpiates

Narrower (15)

ApomorphineAvinzaBrompton mixtureDuramorph

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth.
Morphine is used to treat pain in several medical conditions including cancer. Here we show that morphine, in a concentration… 
Review
2002
Review
2002
Neurobiology of Relapse to Heroin and Cocaine Seeking: A Review
The objective of this article is to review data from studies that used a reinstatement model in rats to elucidate the neural… 
Review
2001
Review
2001
Strategies to manage the adverse effects of oral morphine: an evidence-based report.
Successful pain management with opioids requires that adequate analgesia be achieved without excessive adverse effects. By these… 
Review
1995
Review
1995
Mechanisms of hyperalgesian and morphine tolerance: a current view of their possible interactions
Highly Cited
1992
Highly Cited
1992
Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery.
BACKGROUND Extreme hormonal and metabolic responses to stress are associated with increased morbidity and mortality in sick… 
Highly Cited
1981
Highly Cited
1981
Receptor binding profile of R 41 468, a novel antagonist at 5-HT2 receptors.
Highly Cited
1979
Highly Cited
1979
Suggestive evidence for receptors for morphine and methionine-enkephalin on normal human blood T lymphocytes.
This study reports the in vitro influence of morphine, dextromoramide, levomoramide, and methionine-enkephalin upon normal human… 
Highly Cited
1978
Highly Cited
1978
Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine
NORADRENERGIC neurones of the locus coeruleus (LC; A6 of ref. 1) are inhibited by the systemic or local administration of… 
Highly Cited
1976
Highly Cited
1976
Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat
Highly Cited
1975
Highly Cited
1975
Evidence from rats that morphine tolerance is a learned response.
It is proposed that the direct analgesic effect of morphine becomes attenuated over the course of successive administrations of… 
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