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NOD1 gene

Known as: CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 4, NLRC1, CARD4 
This gene plays a role in both apoptosis and immunity.
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisCaspase ActivationCaspase-Dependent ApoptosisNOD1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular epithelial cell protein known to play a role in host… 
Highly Cited
2009
Highly Cited
2009
XIAP mediates NOD signaling via interaction with RIP2
NOD1 and NOD2 are members of the NOD-like receptor (NLR) protein family that are involved in sensing the presence of pathogens… 
Highly Cited
2008
Highly Cited
2008
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands.
Highly Cited
2008
Highly Cited
2008
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.
Nod1 and Nod2 are intracellular proteins that are involved in host recognition of specific bacterial molecules and are… 
Review
2008
Review
2008
NOD-like receptors (NLRs): bona fide intracellular microbial sensors.
Highly Cited
2007
Highly Cited
2007
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
Highly Cited
2006
Highly Cited
2006
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
Nod1 is a member of family of intracellular proteins that mediate host recognition of bacterial peptidoglycan. To characterize… 
Highly Cited
2005
Highly Cited
2005
Synergistic stimulation of human monocytes and dendritic cells by Toll‐like receptor 4 and NOD1‐ and NOD2‐activating agonists
Muropeptides are degradation products of bacterial peptidoglycan (PG) sensed by nucleotide‐binding oligomerization domain 1 (NOD1… 
Highly Cited
2004
Highly Cited
2004
Muramyldipeptide and diaminopimelic acid‐containing desmuramylpeptides in combination with chemically synthesized Toll‐like receptor agonists synergistically induced production of interleukin‐8 in a…
Two types of synthetic peptidoglycan fragments, diaminopimelic acid (DAP)‐containing desmuramylpeptides (DMP) and… 
Review
2002
Review
2002
Nods: a family of cytosolic proteins that regulate the host response to pathogens.
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