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NGFR protein, human

Known as: Low Affinity Neurotrophin Receptor p75NTR, p75 neurotrophin receptor, human, p75NGFR protein, human 
Tumor necrosis factor receptor superfamily member 16 (427 aa, ~45 kDa) is encoded by the human NGFR gene. This protein plays a role in neurotrophin… 
National Institutes of Health

Related topics

Related topics

22 relations
ApoptosisApoptosis Regulatory ProteinsCytokine Receptor GeneCytokine Signaling Process

Broader (3)

NGFR ProteinNerve Tissue ProteinsReceptors, Nerve Growth Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
Nerve growth factor receptor trkA is down‐regulated during postnatal development by a subset of dorsal root ganglion neurons
Nerve growth factor (NGF), signaling through its receptor tyrosine kinase, TrkA, is required for the survival of all small and… 
Highly Cited
1997
Highly Cited
1997
Autophosphorylation of Activation Loop Tyrosines Regulates Signaling by the TRK Nerve Growth Factor Receptor*
Many receptor tyrosine kinases possess an “activation loop” containing three similarly placed tyrosine autophosphorylation sites… 
Highly Cited
1997
Highly Cited
1997
The Neurotrophin Receptor p75 Binds Neurotrophin-3 on Sympathetic Neurons with High Affinity and Specificity
High-affinity neurotrophin-3 (NT3) receptors have been identified on nerve growth factor (NGF)-dependent sympathetic neurons, but… 
Highly Cited
1992
Highly Cited
1992
Reduced expression of the low affinity nerve growth factor receptor in benign and malignant human prostate tissue and loss of expression in four human metastatic prostate tumor cell lines.
In the human prostate, a low affinity (p75) nerve growth factor (NGF) receptor (NGF-R) localizes to the epithelia while a NGF… 
Highly Cited
1992
Highly Cited
1992
Distribution of nerve growth factor-like protein and nerve growth factor receptor in human benign prostatic hyperplasia and prostatic adenocarcinoma.
Highly Cited
1991
Highly Cited
1991
Dependence of kidney morphogenesis on the expression of nerve growth factor receptor.
Nerve growth factor receptor (NGFR) serves as the binding site for the neurotrophic growth factors. Although NGFR has been found… 
Highly Cited
1991
Highly Cited
1991
Loss of AChE- and NGFr-labeling precedes neuronal death of axotomized septal-diagonal band neurons: Reversal by intraventricular NGF infusion
Highly Cited
1991
Highly Cited
1991
Disruption of cysteine-rich repeats of the p75 nerve growth factor receptor leads to loss of ligand binding.
Highly Cited
1990
Highly Cited
1990
Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein.
Tumor necrosis factor-alpha (TNF-alpha), a protein released by activated macrophages, is involved in a wide variety of human… 
Highly Cited
1985
Highly Cited
1985
Characterization of the human melanoma nerve growth factor receptor.
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