NGFR Protein

Known as: NGFR, gp75, Receptor p75, Neurotropin, Receptor, Nerve Growth Factor 
A low affinity receptor that binds NERVE GROWTH FACTOR; BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; and neurotrophin 4.

Topic mentions per year

Topic mentions per year

1997-2018
0102019972018

Papers overview

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2009
2009
Ligand-mediated dimerization has emerged as a universal mechanism of growth factor receptor activation. Neurotrophins interact… (More)
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2009
2009
Dimerization is recognized as a crucial step in the activation of many plasma membrane receptors. However, a growing number of… (More)
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Highly Cited
2008
Highly Cited
2008
Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Abeta, degeneration of the… (More)
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2008
2008
The multifunctional signaling protein p75 neurotrophin receptor (p75(NTR)) is a central regulator and major contributor to the… (More)
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Highly Cited
2007
Highly Cited
2007
The invasive nature of cancers in general, and malignant gliomas in particular, is a major clinical problem rendering tumors… (More)
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Highly Cited
2005
Highly Cited
2005
Pro- and mature brain-derived neurotrophic factor (BDNF) activate two distinct receptors: p75 neurotrophin receptor (p75NTR) and… (More)
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Highly Cited
2005
Highly Cited
2005
The three known inhibitors of axonal regeneration present in myelin--MAG, Nogo, and OMgp--all interact with the same receptor… (More)
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2004
2004
Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to reduce inflammation and as analgesics by inhibition of cyclooxygenase-2… (More)
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2002
2002
The neurodegenerative changes in Alzheimer's disease (AD) are elicited by the accumulation of beta-amyloid peptides (Abeta… (More)
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Highly Cited
2000
Highly Cited
2000
The mechanisms employed by the p75 neurotrophin receptor (p75NTR) to mediate neurotrophin-dependent apoptosis are poorly defined… (More)
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